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Effects of exercise intensity on anterior cerebral perfusion in prepubertal children Simair, Ryan


Introduction: Although high intensity interval exercise (HIIE) has been well characterized in adults as providing superior systemic vascular adaptions compared to moderate intensity exercise (MIE), there is evidence that HIIE poses a challenge to cerebral hemodynamics. Only one study has investigated the child’s middle cerebral artery (MCA) response to incremental exercise to maximum, and we do not currently understand the cerebrovascular response to either HIIE or continuous MIE in the child. Methods: Nine children (aged 7-11 y; 5 girls) completed either HIIE (six 1-minute cycle ergometer sprints at 90% peak power (Wmax) with 1-minute recovery at 20% Wmax) or MIE (15 minutes at 44% Wmax on a cycle ergometer, matched to HIIE for external work). MCA velocity (MCAv), partial pressure of end tidal carbon dioxide (PETCO₂) and mean arterial pressure (MAP) were measured at baseline, immediately post-, 30 minutes post- and 60 minutes post-exercise. MCAv was also continuously recorded throughout exercise. A repeated measures ANOVA was used to compare changes from baseline across the time-points and between the exercise conditions. Results: The MCAv peaked during the first two minutes in both HIIE (minute 1: +12.10±2.70% & minute 2: +12.65±6.20%; p’s

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