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The use of dupilumab in severe atopic dermatitis during pregnancy: a case report Akhtar, Nabeel H.; Khosravi-Hafshejani, Touraj; Akhtar, Daud; Dhadwal, Gurbir; Kanani, Amin

Abstract

Background Atopic dermatitis is a common chronic skin disease that can occur in pregnancy. Current treatments include topical and systemic glucocorticoids and cyclosporine. Presently, the only biologic approved for atopic dermatitis is dupilumab with limited data available regarding its safety profile in pregnancy. Case presentation We report a case of severe atopic dermatitis treated safely with dupilumab with no adverse maternal or fetal outcomes and resolution of atopic dermatitis postpartum in the absence of maintenance dupilumab therapy. Conclusion Here we demonstrate the safe use of dupilumab in pregnancy. Further research is needed to elucidate the role of dupilumab in the management of atopic dermatitis during pregnancy.

Item Metadata

Title
The use of dupilumab in severe atopic dermatitis during pregnancy: a case report
Creator
Akhtar, Nabeel H.; Khosravi-Hafshejani, Touraj; Akhtar, Daud; Dhadwal, Gurbir; Kanani, Amin
Publisher
BioMed Central
Date Issued
2022-02-03
Description
Background Atopic dermatitis is a common chronic skin disease that can occur in pregnancy. Current treatments include topical and systemic glucocorticoids and cyclosporine. Presently, the only biologic approved for atopic dermatitis is dupilumab with limited data available regarding its safety profile in pregnancy. Case presentation We report a case of severe atopic dermatitis treated safely with dupilumab with no adverse maternal or fetal outcomes and resolution of atopic dermatitis postpartum in the absence of maintenance dupilumab therapy. Conclusion Here we demonstrate the safe use of dupilumab in pregnancy. Further research is needed to elucidate the role of dupilumab in the management of atopic dermatitis during pregnancy.
Subject
Atopic dermatitis; Dupilumab; Pregnancy; Outcome
Genre
Article
Type
Text
Language
eng
Date Available
2022-02-17
Provider
Vancouver : University of British Columbia Library
Rights
Attribution 4.0 International (CC BY 4.0)
DOI
10.14288/1.0406611
URI
http://hdl.handle.net/2429/80845
Affiliation
Medicine, Faculty of; Non UBC; Dermatology and Skin Science, Department of; Medicine, Department of
Citation
Allergy, Asthma & Clinical Immunology. 2022 Feb 03;18(1):9
Publisher DOI
10.1186/s13223-022-00650-w
Peer Review Status
Reviewed
Scholarly Level
Faculty
Copyright Holder
The Author(s)
Rights URI
http://creativecommons.org/licenses/by/4.0/
Aggregated Source Repository
DSpace

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Attribution 4.0 International (CC BY 4.0)