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Studying HPV vaccination and infection through a simplified stochastic model Illing, Hannah; Porter, Imogen

Abstract

While HPV vaccination has been modelled through deterministic and STDSIM models, the use of stochastic models remains relatively low. We developed a unique individual based stochastic model for the spread of HPV in a group of individuals from the ages 15-30 in order to investigate and measure the effects of vaccination scenarios on infection rates, overall immunity, and response to outbreaks. This was done by measuring the number of infected and immune individuals over time, with standard deviations providing indication of predictability. Vaccinating solely females produced marginally higher acquired immunity effects than vaccinating both sexes which resulted in less variability in the frequency of infected individuals. The results of the study support the hypothesis that increasing vaccination rates would decrease HPV prevalence.

Item Metadata

Title
Studying HPV vaccination and infection through a simplified stochastic model
Creator
Illing, Hannah; Porter, Imogen
Date Issued
2021-06-25
Description
While HPV vaccination has been modelled through deterministic and STDSIM models, the use of stochastic models remains relatively low. We developed a unique individual based stochastic model for the spread of HPV in a group of individuals from the ages 15-30 in order to investigate and measure the effects of vaccination scenarios on infection rates, overall immunity, and response to outbreaks. This was done by measuring the number of infected and immune individuals over time, with standard deviations providing indication of predictability. Vaccinating solely females produced marginally higher acquired immunity effects than vaccinating both sexes which resulted in less variability in the frequency of infected individuals. The results of the study support the hypothesis that increasing vaccination rates would decrease HPV prevalence.
Genre
Report
Type
Text
Language
eng
Series
University of British Columbia. Science One Research Projects; University of British Columbia. SCIE 001
Date Available
2021-06-14
Provider
Vancouver : University of British Columbia Library
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
DOI
10.14288/1.0398356
URI
http://hdl.handle.net/2429/78624
Affiliation
Science, Faculty of
Peer Review Status
Unreviewed
Scholarly Level
Undergraduate
Rights URI
http://creativecommons.org/licenses/by-nc-nd/4.0/
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Attribution-NonCommercial-NoDerivatives 4.0 International