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Silver staining of the synapse in the human cerebrum Morrison, George Edward

Abstract

There has been recent tendency on the part of certain investigators, because of their failure to demonstrate boutons terminaux in the cerebral cortex by the silver impregnation methods, to suggest that the pericellular fibers in the cerebral cortex end freely on the cells and that such free terminals are the normal form of synapse in this part of the central nervous system. In the present work a histological study was made of certain areas in the frontal cerebral and the visual cortex to show the presence of normal boutons terminaux. It was demonstrated that boutons occur in these areas in sufficient numbers to indicate that these are the normal means of synapse. The direction which further research should take is suggested.

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