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UBC Theses and Dissertations
Some effects of thyroxine on developing Chum salmon, Oncorhynchus keta, and the comparative action of thiourea, the halides and adrenalin. Dales, Samuel
Abstract
Chum salmon eggs were immersed in thyroxine, in thiourea, in halide salts, and in adrenalin on the day of fertilization and were maintained in these solutions until several months after hatching. All treatments affected growth either favourably or adversely, but only thyroxine and chloride changed body proportions. The changes due to chloride were significantly smaller than those following thyroxine treatment, and it is postulated that they are not “thyroxine-like” in nature. Thiourea inhibited colloid function with the usual hypertrophy and hyperplasia of the gland. Chloride and bromide depressed the heart rate significantly, whilst the other treatments had no effect. Iodide and bromide dispersed melanin pigment but thyroxine concentrated it slightly and adrenalin maximally so that adrenalin treated live fish were very pale. Thyroxine increased markedly the deposition of guanine and must, therefore, accelerate the hydrolysis of nuclear purines. It is concluded that specific effects produced by thyroxine in developing chum salmon are not duplicated by the halides and adrenalin.
Item Metadata
Title |
Some effects of thyroxine on developing Chum salmon, Oncorhynchus keta, and the comparative action of thiourea, the halides and adrenalin.
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Creator | |
Publisher |
University of British Columbia
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Date Issued |
1953
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Description |
Chum salmon eggs were immersed in thyroxine, in thiourea, in halide salts, and in adrenalin on the day of fertilization and were maintained in these solutions until several months after hatching. All treatments affected growth either favourably or adversely, but only thyroxine and chloride changed body proportions. The changes due to chloride were significantly smaller than those following thyroxine treatment, and it is postulated that they are not “thyroxine-like” in nature. Thiourea inhibited colloid function with the usual hypertrophy and hyperplasia of the gland. Chloride and bromide depressed the heart rate significantly, whilst the other treatments had no effect. Iodide and bromide dispersed melanin pigment but thyroxine concentrated it slightly and adrenalin maximally so that adrenalin treated live fish were very pale. Thyroxine increased markedly the deposition of guanine and must, therefore, accelerate the hydrolysis of nuclear purines. It is concluded that specific effects produced by thyroxine in developing chum salmon are not duplicated by the halides and adrenalin.
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Genre | |
Type | |
Language |
eng
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Date Available |
2012-02-14
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Provider |
Vancouver : University of British Columbia Library
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Rights |
For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use.
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DOI |
10.14288/1.0106464
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URI | |
Degree (Theses) | |
Program (Theses) | |
Affiliation | |
Degree Grantor |
University of British Columbia
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Campus | |
Scholarly Level |
Graduate
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Aggregated Source Repository |
DSpace
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Item Media
Item Citations and Data
Rights
For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use.