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Some metabolic effects of synthetic sodium thyroxine, thiourea and methyl testosterone on the commoon goldfish Gardner, Robert Renwick

Abstract

A group of five goldfish, Carassius auratus, treated ten and sixteen days with a 1: 3,980,000 concentration of synthetic sodium thyroxine during the winter, had their oxygen consumption significantly raised. Five goldfish treated with .03 per cent thiourea for the same lengths of time during the same period had their oxygen consumption significantly depressed. Two series of similar treatments of three, seven, fourteen and twenty-one days duration throughout the summer did not statistically alter the oxygen consumption and ammonia excretion. Treatments with a 1: 1500,000 concentration of methyl testosterone for three, seven, fourteen and twenty-one days statistically elevated the oxygen consumption and ammonia excretion. The thiourea, synthetic sodium thyroxine and methyl testosterone treatments for three, seven, fourteen and twenty-one days did not appreciably alter the total lipid and moisture content of the goldfish tissue. These treatments do not appear to alter the oxygen carbon dioxide tension at death nor the length of time to asphyxiate the goldfish.

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