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The amerlioration of experimental hypertension with granulestin Barker, Robert

Abstract

Granulestin, added to the basal diet of the rat, was found to be effective in lowering the blood pressure where-an elevation had been obtained by nicotine injections and choline deficiency. No significant decrease in blood pressure could be found in the case of male or female rats treated with estradiol dipropionate. Caffeine and desoxycorticosterone acetate injections were found to result in a slight transient hypertension and the effectiveness of Granulestin feeding could not be tested.

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