Open Collections will undergo maintenance on Thursday, July 24th, 2025. The site will not be available from 8:00 AM - 9:00 AM PST and performance may be impacted from 9:00 AM - 12:00 PM PST.

UBC Theses and Dissertations

UBC Theses Logo

UBC Theses and Dissertations

DNA sequence and structure analysis of the Drosophila gene Polyhomeotic Daly, Mark K.

Abstract

polyhomeotic is a gene of the Polycomb-group required for proper segment determination in Drosophila. Genetic and molecular analysis has shown that ph has a repetetive structure. The DNA sequence presented here shows that ph consists of a direct tandem duplication with very high sequence conservation. Analysis of the sequence has revealed several conserved open reading frames and splice junctions, putative transcriptional promoter and terminator sequences, polyadenylation signals and translational start signals. In addition, the DNA sequence shows that ph contains a zinc finger sequence in each repeat. This suggests that ph may encode a DNA-binding protein.

Item Media

Item Citations and Data

Rights

For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use.