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UBC Theses and Dissertations

The genetic analysis of factors influencing the lethality associated with the scute inversions of Drosophila melanogaster Johnson, Carey


It has been previously established that inviability is associated with X/0 males carrying a scute inversion X chromosome. Explanations of this phenomenon suggest that the lethality may be due to a position effect suppression of the rRNA cistrons. This thesis provides an alternative explanation of the scute X/0 lethality and provides support for the primary function of the scute locus. These studies indicate that the lethality associated with the scute X/0 genotype is conditional and dependent upon the parental origin of the X chromosome. Numerous experiments indicate that the lethality results from a disfunction of the scute locus rather than the rRNA cistrons.

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