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The effect of DDT upon the metabolism of estradiol in coho salmon (Oncorhynchus kisutch) Harvey, Brian John

Abstract

In the first experiment, sexually immature male and female coho salmon were exposed for 21 days to dietary DDT at a level of 10 or 100 parts per million (ppm), or to methoxychlor at a level of 100 ppm. Exposure to 100 ppm DDT was found to increase the level of liver microsomal Cytochrome P-450 from a control level of 1.32 ± .04 nmoles/1000 mg liver to a level of 1.98 ± .04 nmoles/1000 mg liver, a statistically significant difference (P

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