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UBC Theses and Dissertations

Antimicrobial resistance in invasive pneumococcal disease Winters, Meghan Lesley

Abstract

Antimicrobial resistance in Streptococcus pneumoniae has increased in recent decades at a frightening pace. The infant conjugate vaccine program, introduced in BC in 2003, is a tool for the control of invasive pneumococcal disease (IPD) with substantial potential to combat antimicrobial resistance. The first phase of this thesis linked surveillance programs at the BC Centre for Disease Control and the National Centre for Streptococcus to evaluate recent trends in IPD incidence, serotype distribution, and antimicrobial resistance. Based on 1,288 reported cases of IPD over 2002-2005, there was a significant decrease in the incidence in children

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