- Library Home /
- Search Collections /
- Open Collections /
- Browse Collections /
- UBC Theses and Dissertations /
- Anti-invasive activity of Bovine colostrum and whey...
Open Collections
UBC Theses and Dissertations
UBC Theses and Dissertations
Anti-invasive activity of Bovine colostrum and whey proteins against Salmonella typhimurium Noei, Azita Madadi
Abstract
Bovine colostrum, non-immunoglobulin G (non-IgG) fraction, obtained after passing colostral whey through a protein G-agarose affinity chromatography column, and selected whey proteins (a-lactalbumin, P-lactoglobulin, lactoferrin and lactoperoxidase) were tested for anti-invasive activity against Salmonella Typhimurium SL 1344 invasion of HeLa cells. Bovine colostrum and non-IgG fraction decreased S. Typhimurium invasion of cultured HeLa cells by 98 and 66% respectively. In an attempt to find the anti-invasive compound(s) in non-IgG fraction of bovine colostral whey, lactoferrin, a-lactalbumin, Blactoglobulin and lactoperoxidase were tested for their effect on HeLa cell invasion by S. Typhimurium. All tested whey proteins except lactoperoxidase, at concentrations up to 10 mg mL⁻¹, significantly (p
Item Metadata
Title |
Anti-invasive activity of Bovine colostrum and whey proteins against Salmonella typhimurium
|
Creator | |
Publisher |
University of British Columbia
|
Date Issued |
2003
|
Description |
Bovine colostrum, non-immunoglobulin G (non-IgG) fraction, obtained after passing colostral whey through a protein G-agarose affinity chromatography column, and selected whey proteins (a-lactalbumin, P-lactoglobulin, lactoferrin and lactoperoxidase) were tested for anti-invasive activity against Salmonella Typhimurium SL 1344 invasion of HeLa cells. Bovine colostrum and non-IgG fraction decreased S. Typhimurium invasion of cultured HeLa cells by 98 and 66% respectively. In an attempt to find the anti-invasive compound(s) in non-IgG fraction of bovine colostral whey, lactoferrin, a-lactalbumin, Blactoglobulin and lactoperoxidase were tested for their effect on HeLa cell invasion by S. Typhimurium. All tested whey proteins except lactoperoxidase, at concentrations up to 10 mg mL⁻¹, significantly (p
|
Extent |
10788120 bytes
|
Genre | |
Type | |
File Format |
application/pdf
|
Language |
eng
|
Date Available |
2009-11-12
|
Provider |
Vancouver : University of British Columbia Library
|
Rights |
For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use.
|
DOI |
10.14288/1.0091314
|
URI | |
Degree | |
Program | |
Affiliation | |
Degree Grantor |
University of British Columbia
|
Graduation Date |
2003-11
|
Campus | |
Scholarly Level |
Graduate
|
Aggregated Source Repository |
DSpace
|
Item Media
Item Citations and Data
Rights
For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use.