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UBC Theses and Dissertations

The role of OprH in the uptake of antibiotics across the outer membrane of Pseudomonas aeruginosa Young, Michele Louise


The oprH gene of Pseudomonas aeruginosa was mutated by inserting a 1.4 kilobase pair fragment, encoding tetracycline resistance, into the cloned gene followed by homologous recombination into the P. aeruginosa chromosome. Growth of the resultant oprH

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