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- Arachidonic acid as a potential intracellular regulator...
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Arachidonic acid as a potential intracellular regulator of aromatase activity in human term trophoblast Lin, Show Whei
Abstract
The potential role of arachidonic acid as an intracellular regulator of aromatase activity of human term trophoblast was investigated in short term (3 h) incubations. Melittin, a known activator of phospholipase A₂,suppressed the aromatase activity of physically dissociated trophoblast cells in a dose-dependent manner. Indomethacin (10⁻⁴M), a cyclooxygenase inhibitor of arachidonic acid metabolism, suppressed aromatase activity and potentiated the inhibitory effect of melittin (P
Item Metadata
Title |
Arachidonic acid as a potential intracellular regulator of aromatase activity in human term trophoblast
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Creator | |
Publisher |
University of British Columbia
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Date Issued |
1992
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Description |
The potential role of arachidonic acid as an intracellular regulator of aromatase activity of human term trophoblast was investigated in short term (3 h) incubations. Melittin, a known activator of phospholipase A₂,suppressed the aromatase activity of physically dissociated trophoblast cells in a dose-dependent manner. Indomethacin (10⁻⁴M), a cyclooxygenase inhibitor of arachidonic acid metabolism, suppressed aromatase activity and potentiated the inhibitory effect of melittin (P
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Extent |
3850389 bytes
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Genre | |
Type | |
File Format |
application/pdf
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Language |
eng
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Date Available |
2008-09-16
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Provider |
Vancouver : University of British Columbia Library
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Rights |
For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use.
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DOI |
10.14288/1.0086417
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URI | |
Degree | |
Program | |
Affiliation | |
Degree Grantor |
University of British Columbia
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Graduation Date |
1992-05
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Campus | |
Scholarly Level |
Graduate
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Aggregated Source Repository |
DSpace
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Item Media
Item Citations and Data
Rights
For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use.