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UBC Theses and Dissertations
Studies of tumor promoters and drug-metabolic enzymes in hamster buccal pouch mucosa Zhang, Dong M.
Abstract
Lack of tumor promoters has been the major obstacle in the use of the hamster buccal pouch mucosa (HBPM) model. Two experiments were designed to investigate the effects of two new mouse skin tumor promoters, okadaic acid (OA) and methyl methanesulfonate (MMS), on HBPM. Short term effects of OA were studied. A single application of10 1.1.g of OA in 0.1 ml of acetone produced marked inflammation as well as an increased mitotic rate (p
Item Metadata
| Title |
Studies of tumor promoters and drug-metabolic enzymes in hamster buccal pouch mucosa
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| Creator | |
| Publisher |
University of British Columbia
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| Date Issued |
1993
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| Description |
Lack of tumor promoters has been the major obstacle in the use of the hamster buccal pouch mucosa (HBPM) model. Two experiments were designed to investigate the effects of two new mouse skin tumor promoters, okadaic acid (OA) and methyl methanesulfonate (MMS), on HBPM.
Short term effects of OA were studied. A single application of10 1.1.g of OA in 0.1 ml of acetone produced marked inflammation as well as an increased mitotic rate (p
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| Extent |
14904361 bytes
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| Genre | |
| Type | |
| File Format |
application/pdf
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| Language |
eng
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| Date Available |
2008-09-22
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| Provider |
Vancouver : University of British Columbia Library
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| Rights |
For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use.
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| DOI |
10.14288/1.0086188
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| URI | |
| Degree | |
| Program | |
| Affiliation | |
| Degree Grantor |
University of British Columbia
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| Graduation Date |
1993-05
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| Campus | |
| Scholarly Level |
Graduate
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| Aggregated Source Repository |
DSpace
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Item Citations and Data
Rights
For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use.