- Library Home /
- Search Collections /
- Open Collections /
- Browse Collections /
- UBC Theses and Dissertations /
- Creatine phosphokinase: in vitro activity modification...
Open Collections
UBC Theses and Dissertations
UBC Theses and Dissertations
Creatine phosphokinase: in vitro activity modification and proteolysis with calpain Arthur, Gavin D.
Abstract
The purpose of this study was to determine if the muscle isoform of the energy
transmitting kinase; Creatine Phosphokinase (CPK - EC N° 2.7.3.2) MM-isozyme, is a
substrate for calcium activated neutral protease (CANP - EC N° 3.4.22.17). CPK
activity was measured under three different conditions: (1) control assay; (2) with 5mM
Ca²⁺,(5x10⁻³Ca²⁺j; (3) with 5mM Ca²⁺ and a range of CANP amounts from 10 to
lOOug. 5mM Ca²⁺ consistently caused significant inhibition of the CPK activity to
36% of control (p
Item Metadata
| Title |
Creatine phosphokinase: in vitro activity modification and proteolysis with calpain
|
| Creator | |
| Publisher |
University of British Columbia
|
| Date Issued |
1994
|
| Description |
The purpose of this study was to determine if the muscle isoform of the energy
transmitting kinase; Creatine Phosphokinase (CPK - EC N° 2.7.3.2) MM-isozyme, is a
substrate for calcium activated neutral protease (CANP - EC N° 3.4.22.17). CPK
activity was measured under three different conditions: (1) control assay; (2) with 5mM
Ca²⁺,(5x10⁻³Ca²⁺j; (3) with 5mM Ca²⁺ and a range of CANP amounts from 10 to
lOOug. 5mM Ca²⁺ consistently caused significant inhibition of the CPK activity to
36% of control (p
|
| Extent |
1915469 bytes
|
| Genre | |
| Type | |
| File Format |
application/pdf
|
| Language |
eng
|
| Date Available |
2009-02-25
|
| Provider |
Vancouver : University of British Columbia Library
|
| Rights |
For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use.
|
| DOI |
10.14288/1.0077301
|
| URI | |
| Degree (Theses) | |
| Program (Theses) | |
| Affiliation | |
| Degree Grantor |
University of British Columbia
|
| Graduation Date |
1994-05
|
| Campus | |
| Scholarly Level |
Graduate
|
| Aggregated Source Repository |
DSpace
|
Item Media
Item Citations and Data
Rights
For non-commercial purposes only, such as research, private study and education. Additional conditions apply, see Terms of Use https://open.library.ubc.ca/terms_of_use.