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The effects of intermittent exposure to hyperbaric oxygen for the treatment of an acute soft tissue injury Babul, Shelina


This study examined the effects of intermittent exposure to hyperbaric oxygen therapy (HBO) for the treatment of delayed onset muscle soreness (DOMS). It is apparent in the literature that a great deal of controversy exists in using this form of therapy to treat tissue injuries. It was hypothesized that subjects exposed to hyperbaric oxygen would recover from DOMS faster than subjects exposed to normoxic air. Sixteen sedentary, female university students participated in the study and were randomly assigned to either an experimental or control group. All subjects performed 300 maximal voluntary eccentric contractions (30 sets of 10 repetitions/minute) of their non-dominant leg (110° - 35° of knee flexion) at a slow speed (30° per second) on the KinCom Dynamometer, to elicit muscle damage and injury. HBO treatments consisted of 100% oxygen for 60 minutes at 2.0 ATA while the control group received 21 % oxygen at 1.2 ATA for the same amount of time. Both groups received treatment immediately after the induction of DOMS and each day after for a period of 4 days [day 2 post-exercise thru day 5 post-exercise]. Dependent variables (perceived muscle soreness, isokinetic strength, quadriceps circumference, creatine kinase (CK), interleukin-6 (IL-6) and malondialdehyde (MDA) were assessed baseline (preexercise, day 1), 4 hours post-exercise (day 2), 24 hours post-exercise (day 3), 48 hours post-exercise (day 4) and 72 hours post-exercise (day 5). MRI [T2 relaxation time/STIR]) was assessed baseline (day 1), 24 hours post-exercise (day 3) and 72 hours post-exercise (day 5). Isokinetic strength (p

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