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Exploring spatial heterogeneity of radiation dose deposition with radiochromic film and Raman spectroscopy Gao, Wanye

Abstract

This thesis considers dosimetric analysis of EBT-3 films using Raman spectroscopy, aiming to use spectral data to investigate spatial heterogeneity associated with radiation exposure at about the cellular-level of granularity. Herein, we identify two principal peaks serving as indicators of dose response, which display obvious Raman intensity variations for different dose levels. In contrast, the Raman intensity for peaks associated with polyester have shown consistency across dose levels. To further explore the spatial patterns, we consider Moran’s I and Haralick features, which provide similar measures between dose-response peaks and Monte Carlo simulated radiation. This reinforces the hypothesis that the principal peaks are detecting radiation- induced changes on the film-based dosimeter.

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Attribution-NoDerivatives 4.0 International