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Ketter, Nicole

University of British Columbia

Background: Cardiometabolic multimorbidity, the diagnosis of ≥ 2 of stroke, heart disease and diabetes, is associated with a multiplicative mortality risk and numerous poor health outcomes. As an emerging and significant health problem, the management and prevention of cardiometabolic multimorbidity has not been sufficiently studied. The overarching purpose of this multi-methods MSc research is to develop an understanding of cardiometabolic multimorbidity in Canada that may lead to improved prevention and management strategies. Methods: Study 1) This observational, secondary-analysis utilized data from the Canadian Longitudinal Study on Aging. We used descriptive statistics to determine 3-year cardiometabolic multimorbidity onset and logistic regression analyses to quantify the association between functioning and disability variables (depressive symptoms, eyesight, pain, blood pressure, activity limitation, and participation) and 3-year cardiometabolic multimorbidity onset. Study 2) We used a qualitative description study design to elucidate the lived experiences of cardiometabolic multimorbidity and investigate the self-management of medical, role and emotional tasks. Data from the interviews were transcribed verbatim and analyzed thematically, as per Braun & Clarke’s methodology. Results: Study 1) 41,841 participants were included, representing a weighted total of 13,741,119 individuals. The incidence of 3-year cardiometabolic multimorbidity onset was 2%, representing 247,683 Canadians. After adjusting for covariates, having high depressive symptoms, pain, fair vision, high blood pressure, and mild activity limitations were significantly associated with 3-year cardiometabolic multimorbidity onset. Study 2) Thirteen participants described the complex nature of living with and managing cardiometabolic multimorbidity, identifying four themes that describe the self-management of medical, role and emotional tasks through motivation, adaptation, and resiliency. Conclusions: This research significantly advances our understanding of cardiometabolic multimorbidity in Canada, underscoring its complexity and the need for holistic prevention and management strategies. Study 1's findings reveal novel risk factors of cardiometabolic multimorbidity onset, highlighting areas for targeted interventions. Study 2 offers valuable insights into the lived experiences of individuals with cardiometabolic multimorbidity, illustrating how motivation, adaptability and resiliency influence self-management. Collectively, these studies emphasize the need for integrated healthcare strategies that consider the prevention and management of cardiometabolic multimorbidity holistically, ultimately improving health outcomes for Canadians.

Text

2024-06-06

Attribution-NonCommercial-NoDerivatives 4.0 International

http://hdl.handle.net/2429/88418

Rehabilitation Sciences

University of British Columbia

UBCV

http://creativecommons.org/licenses/by-nc-nd/4.0/