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Readout and data analysis circuits for silicon photonic evanescent field biosensors Panda, Sarthak
Abstract
Silicon Photonic (SiP) evanescent field biosensors exhibit promising potential for developing low-cost medical diagnostics. With modern silicon processes, hundreds of such sensors can be integrated, enabling simultaneous detection and processing of multiple biomarkers. Most state-of-the-art evanescent field sensors use resonance peak tracking to measure biomolecule concentrations. The simplicity of optics in such sensors makes them a perfect candidate for commercial scalability. However, they require complex processing to filter useful information from data distorted by noise and sensor artifacts. Contemporary sensors often rely on discrete computing units, rendering the system expensive and impractical for point-of-care (PoC) applications. Through innovative optics, coherent biosensors have paved the pathway for simplified electronics readout. This being said, achieving comparable performance to peak tracking sensors requires substantial changes in the design of coherent electronic readouts. For the global success of evanescent field sensors, it is imperative to integrate on-chip readouts without compromising performance. This thesis addresses this challenge through two main objectives. Firstly, a hardware-aware on-chip sensor-data processor is implemented for peak tracking evanescent field sensors, ensuring performance parity with discrete processors. Secondly, an electronic readout system is designed to improve the performance of coherent biosensors.
Item Metadata
Title |
Readout and data analysis circuits for silicon photonic evanescent field biosensors
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Creator | |
Supervisor | |
Publisher |
University of British Columbia
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Date Issued |
2024
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Description |
Silicon Photonic (SiP) evanescent field biosensors exhibit promising potential
for developing low-cost medical diagnostics. With modern silicon
processes, hundreds of such sensors can be integrated, enabling simultaneous
detection and processing of multiple biomarkers. Most state-of-the-art
evanescent field sensors use resonance peak tracking to measure biomolecule
concentrations. The simplicity of optics in such sensors makes them a perfect
candidate for commercial scalability. However, they require complex
processing to filter useful information from data distorted by noise and sensor
artifacts. Contemporary sensors often rely on discrete computing units,
rendering the system expensive and impractical for point-of-care (PoC) applications.
Through innovative optics, coherent biosensors have paved the pathway
for simplified electronics readout. This being said, achieving comparable
performance to peak tracking sensors requires substantial changes in the
design of coherent electronic readouts.
For the global success of evanescent field sensors, it is imperative to integrate
on-chip readouts without compromising performance. This thesis
addresses this challenge through two main objectives. Firstly, a hardware-aware
on-chip sensor-data processor is implemented for peak tracking evanescent
field sensors, ensuring performance parity with discrete processors. Secondly,
an electronic readout system is designed to improve the performance
of coherent biosensors.
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Genre | |
Type | |
Language |
eng
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Date Available |
2024-04-10
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Provider |
Vancouver : University of British Columbia Library
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Rights |
Attribution-NonCommercial-NoDerivatives 4.0 International
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DOI |
10.14288/1.0441290
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URI | |
Degree | |
Program | |
Affiliation | |
Degree Grantor |
University of British Columbia
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Graduation Date |
2024-05
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Campus | |
Scholarly Level |
Graduate
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Rights URI | |
Aggregated Source Repository |
DSpace
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Rights
Attribution-NonCommercial-NoDerivatives 4.0 International