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The effect of oxygen supplementation on brachial artery hemodynamics and vascular function during trekking ascent to high altitude Vizcardo-Galindo, Gustavo
Abstract
High altitude trekking alters upper limb hemodynamics and reduces brachial artery vascular function in lowlanders. However, whether these changes are reversible with the correction of hypoxia is unknown. We investigated the impact of 15 minutes of oxygen supplementation (O₂) on brachial artery hemodynamics, reactive hyperemia (microvascular function) and flow-mediated dilation (FMD; endothelial function). Healthy male participants (aged 21-42 years) were examined prior to and with O₂ at 3440m (day 4 at high altitude; n=7), 4371m (day 7; n=7), and 5050m (day 10; n=12) using Duplex ultrasound. At 3440m, O₂ decreased brachial artery diameter (-5±5%; P=0.04), baseline blood flow (-44±15%; P
Item Metadata
Title |
The effect of oxygen supplementation on brachial artery hemodynamics and vascular function during trekking ascent to high altitude
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Creator | |
Supervisor | |
Publisher |
University of British Columbia
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Date Issued |
2022
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Description |
High altitude trekking alters upper limb hemodynamics and reduces brachial artery vascular function in lowlanders. However, whether these changes are reversible with the correction of hypoxia is unknown. We investigated the impact of 15 minutes of oxygen supplementation (O₂) on brachial artery hemodynamics, reactive hyperemia (microvascular function) and flow-mediated dilation (FMD; endothelial function). Healthy male participants (aged 21-42 years) were examined prior to and with O₂ at 3440m (day 4 at high altitude; n=7), 4371m (day 7; n=7), and 5050m (day 10; n=12) using Duplex ultrasound. At 3440m, O₂ decreased brachial artery diameter (-5±5%; P=0.04), baseline blood flow (-44±15%; P
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Genre | |
Type | |
Language |
eng
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Date Available |
2023-01-16
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Provider |
Vancouver : University of British Columbia Library
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Rights |
Attribution-NonCommercial-NoDerivatives 4.0 International
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DOI |
10.14288/1.0423051
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URI | |
Degree (Theses) | |
Program (Theses) | |
Affiliation | |
Degree Grantor |
University of British Columbia
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Graduation Date |
2023-02
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Campus | |
Scholarly Level |
Graduate
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Rights URI | |
Aggregated Source Repository |
DSpace
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Item Citations and Data
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International