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Investigating the factors influencing survival after out-of-hospital cardiac arrest: sex-based differences in resuscitation and outcomes Awad, Emad Mohamad
Abstract
The objective of the studies in this dissertation was to examine the effects of sex on out-of-hospital cardiac arrest (OHCA) interventions and outcomes, including survival to hospital discharge, one-year survival, and survival with favourable neurological function. Data were obtained from the British Columbia (BC) Cardiac Arrest Registry, Population Data BC, and a multi-centre clinical trial carried out in the USA and Canada. Analysis methods comprised logistic regression, survival analysis, and multilevel analysis. The first study was an analysis of a cohort of 7,398 adults with OHCA in BC and showed that in patients who did not achieve prehospital ROSC, males had 1.2-fold greater odds of being transported to hospital compared to females (95% CI 1.04, 1.37). The second study was a retrospective analysis of 8,115 OHCA cases in BC and revealed that females had greater adjusted odds of ROSC (OR 1.29, 95% CI 1.15 – 1.42, p
Item Metadata
| Title |
Investigating the factors influencing survival after out-of-hospital cardiac arrest: sex-based differences in resuscitation and outcomes
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| Creator | |
| Supervisor | |
| Publisher |
University of British Columbia
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| Date Issued |
2021
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| Description |
The objective of the studies in this dissertation was to examine the effects of sex on out-of-hospital cardiac arrest (OHCA) interventions and outcomes, including survival to hospital discharge, one-year survival, and survival with favourable neurological function. Data were obtained from the British Columbia (BC) Cardiac Arrest Registry, Population Data BC, and a multi-centre clinical trial carried out in the USA and Canada. Analysis methods comprised logistic regression, survival analysis, and multilevel analysis.
The first study was an analysis of a cohort of 7,398 adults with OHCA in BC and showed that in patients who did not achieve prehospital ROSC, males had 1.2-fold greater odds of being transported to hospital compared to females (95% CI 1.04, 1.37).
The second study was a retrospective analysis of 8,115 OHCA cases in BC and revealed that females had greater adjusted odds of ROSC (OR 1.29, 95% CI 1.15 – 1.42, p
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| Genre | |
| Type | |
| Language |
eng
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| Date Available |
2021-09-15
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| Provider |
Vancouver : University of British Columbia Library
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| Rights |
Attribution-NonCommercial-NoDerivatives 4.0 International
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| DOI |
10.14288/1.0402152
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| URI | |
| Degree (Theses) | |
| Program (Theses) | |
| Affiliation | |
| Degree Grantor |
University of British Columbia
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| Graduation Date |
2021-11
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| Campus | |
| Scholarly Level |
Graduate
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| Rights URI | |
| Aggregated Source Repository |
DSpace
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Rights
Attribution-NonCommercial-NoDerivatives 4.0 International