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The role of endogenous retinoic acid in jaw development Fan, Churmy Yong
Abstract
The aim of this thesis is to study the effects of reducing retinoic acid (RA) levels in the embryonic face on jaw morphogenesis. One member of the Cytochrome P26 class of enzymes, CYP26A1, which degrades retinol products, was locally overexpressed in chicken embryos. I hypothesized that lowering RA levels would either affect jaw patterning, cell survival and/or cytodifferentiation. Chicken embryos at stage 15 and 20 (E2.5, 3.5) were injected with RCAS
Item Metadata
Title |
The role of endogenous retinoic acid in jaw development
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Creator | |
Publisher |
University of British Columbia
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Date Issued |
2011
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Description |
The aim of this thesis is to study the effects of reducing retinoic acid (RA) levels in the embryonic face on jaw morphogenesis. One member of the Cytochrome P26 class of enzymes, CYP26A1, which degrades retinol products, was locally overexpressed in chicken embryos. I hypothesized that lowering RA levels would either affect jaw patterning, cell survival and/or cytodifferentiation. Chicken embryos at stage 15 and 20 (E2.5, 3.5) were injected with RCAS
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Genre | |
Type | |
Language |
eng
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Date Available |
2011-09-19
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Provider |
Vancouver : University of British Columbia Library
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Rights |
Attribution-ShareAlike 3.0 Unported
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DOI |
10.14288/1.0072224
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URI | |
Degree | |
Program | |
Affiliation | |
Degree Grantor |
University of British Columbia
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Graduation Date |
2011-11
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Campus | |
Scholarly Level |
Graduate
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Rights URI | |
Aggregated Source Repository |
DSpace
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Item Citations and Data
Rights
Attribution-ShareAlike 3.0 Unported