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Chin, Esther

INTRODUCTION: Although chronic urogenital schistosomiasis infection is known to cause bladder fibrosis, data pertaining to the effect of schistosomiasis on vesicovaginal fistula (VVF) repair outcome is limited. METHODS: This retrospective chart review aimed to assess the correlation between chronic schistosomiasis infection, determined by bladder biopsies, and VVF repair outcomes at an urban hospital in Angola. Other objectives were to quantify the prevalence of chronic schistosomiasis among patients with VVF and to assess agreement between pelvic x-rays and bladder biopsies for chronic schistosomiasis diagnosis. Data were collected on patients who underwent VVF repair between June 1, 2022 and November 30, 2022 including: age, number of previous fistula repairs, Goh classification of fistula repair, x-ray and biopsy results, fistula repair outcome, perioperative complications, and postoperative incontinence. Age and number of previous repairs were described using means with standard deviations. Goh classification, x-ray and biopsy results, fistula repair outcome, perioperative complications, and postoperative incontinence were described using frequencies. Parametric and non-parametric tests and Cohen’s Kappa were calculated using R software and Excel. RESULTS: Of the 76 charts retrieved, 60 met inclusion criteria. The overall fistula repair failure rate was 26.7% (n=16). There was no statistically significant difference in the fistula repair failure rate between those with (26.9%) and without (26.5%) evidence of chronic schistosomiasis infection (χ² = 2.33 e-31, p=1, 95% CI -0.30 to 0.28). The prevalence of chronic 4 schistosomiasis was 43.3%. There was no agreement between x-ray and biopsy in diagnosing chronic schistosomiasis infection (Cohen’s Kappa = 0.23, 95% CI -0.001 to 0.47). CONCLUSION: There was no statistically significant difference in the chance of fistula repair failure between those with evidence of chronic schistosomiasis infection and those without.

Text

University of British Columbia. SURG 560

Vancouver : University of British Columbia Library

10.14288/1.0430561

Medicine, Faculty of

Unreviewed

http://creativecommons.org/licenses/by-nc-nd/4.0/