UBC Graduate Research

Productivity Losses and Costs in the Less-Common Systemic Autoimmune Rheumatic Diseases McCormick, Natalie; Marra, Carlo A.; Avina-Zubieta, J. Antonio

Abstract

Purpose of Review: We synthesized the literature on productivity losses and costs in the less-common systemic autoimmune rheumatic diseases: Sjogren’s syndrome (SjS), systemic sclerosis (SSc), poly/dermatomyositis (PM/DM), and systemic vasculitides (SV). Recent Findings: Of 29 studies located, 12 were published 2012-onwards (SSc=6, SjS=2, PM/DM=2, SV=2). In these, 25% of PM/DM, and 21%-26% of SV, were work disabled, 22% of SSc stopped work within three years of diagnosis, and annual costs of absenteeism in SSc averaged $12,024 2017 USD. Very few studies reported on costs, presenteeism (working at reduced levels), or unpaid productivity loss. Across multiple SARDs, major drivers of lost productivity were generalised items like pain, depression, and fatigue, rather than disease-specific factors. Summary: Evidence suggests that work disability is common in SSc and strikes quickly. However in SSc and other SARDs, more comprehensive estimates are needed, which include absenteeism and presenteeism from paid and unpaid work, costs, and drivers of productivity loss.

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Attribution-NonCommercial-NoDerivatives 4.0 International