UBC Graduate Research

Chemotherapy induced cardiomyopathy : what primary care providers should know Narayan, Jane Jayvena

Abstract

As the efficacy of cancer treatments improve, the number of long-term cancer survivors have increased. The concept of cancer survivorship exacerbates the need for primary care providers (PCPs) to identify and treat the potential long-term sequela of chemotoxicity. Amid numerous long-term complications of chemotherapeutic agents, cardiovascular toxicities have been extensively documented in the literature with chemotherapy induced cardiomyopathy (CIC) as one of the leading cardiovascular complications. Guidelines and recommendations are inconsistent regarding the long-term care of this specialized population, yet consensus does exist that if detected early, morbidity and mortality resulting from cardiomyopathy within this population can be improved. This literature review provides PCPs with knowledge in 5 main areas: 1. the clinical definition of CIC and inducing agents, 2. populations at risk, 3. methods and frequency for surveillance, 4. essential clinical assessments and education to provide to patients, and 5. appropriate referral and treatment options. The information obtained from guidelines and research studies was developed into an informational poster and presented at the British Columbia Nurse Practitioner Association’s (BCNPA) annual conference to disseminate evidence-based knowledge regarding the awareness CIC. With increased awareness of this complication it is anticipated that PCPs will be able to promptly identify at-risk patients, provide effective screening and initiate prompt consultations to the appropriate specialty in attempts to improve overall outcomes in cancer survivors.

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Attribution-NonCommercial-NoDerivatives 4.0 International