- Library Home /
- Search Collections /
- Open Collections /
- Browse Collections /
- UBC Faculty Research and Publications /
- Serosurvey of Anaplasma phagocytophilum, Babesia microti,...
Open Collections
UBC Faculty Research and Publications
Serosurvey of Anaplasma phagocytophilum, Babesia microti, and Ehrlichia chaffeensis in Quilombola Communities of Southern Brazil França, Danilo Alves de; Kmetiuk, Louise Bach; Silva, Filipe Pereira da; Panazzolo, Giovanni Kalempa; Biondo, Leandro Meneguelli; Domingues, Orlei José; Fávero, Giovani Marino; Duré, Ana Íris de Lima; Biondo, Alexander Welker
Abstract
Although quilombola individuals and their dogs may be exposed to hemoparasites such as A. phagocytophilum, B. microti, and E. chaffeensis, no study to date has been conducted in these populations. The aim of this study was to investigate the presence of antibodies against Anaplasma phagocytophilum, Babesia microti, and Ehrlichia chaffeensis in humans and dogs from quilombola communities in Brazil. Serum samples from humans and dogs were collected from four rural quilombola communities and analyzed using indirect immunofluorescence assays. The results revealed antibody levels of 8% for A. phagocytophilum, 3% for B. microti, and 1% for E. chaffeensis in humans and 60%, 50%, and 65%, respectively, in dogs. Notably, women were significantly more likely to be seropositive for A. phagocytophilum than men (p = 0.0289). Dogs from the Serra do Apon community more commonly had A. phagocytophilum (p = 0.0477) and B. microti (p = 0.0448) than those from the other areas. To the best of our knowledge, this is the first study to report human exposure to A. phagocytophilum and the ocurrence of B. microti in Brazil. The antibody level of vector-borne diseases in humans is a public health concern, particularly in vulnerable populations and rural areas. The dogs were universally hosted Rhipicephalus sanguineus ticks, suggesting their possible role in transmission. Thus, further epidemiological surveillance studies should be conducted in vulnerable populations to mitigate the impact of such zoonotic diseases.
Item Metadata
| Title |
Serosurvey of Anaplasma phagocytophilum, Babesia microti, and Ehrlichia chaffeensis in Quilombola Communities of Southern Brazil
|
| Creator | |
| Publisher |
Multidisciplinary Digital Publishing Institute
|
| Date Issued |
2025-03-26
|
| Description |
Although quilombola individuals and their dogs may be exposed to hemoparasites such as A. phagocytophilum, B. microti, and E. chaffeensis, no study to date has been conducted in these populations. The aim of this study was to investigate the presence of antibodies against Anaplasma phagocytophilum, Babesia microti, and Ehrlichia chaffeensis in humans and dogs from quilombola communities in Brazil. Serum samples from humans and dogs were collected from four rural quilombola communities and analyzed using indirect immunofluorescence assays. The results revealed antibody levels of 8% for A. phagocytophilum, 3% for B. microti, and 1% for E. chaffeensis in humans and 60%, 50%, and 65%, respectively, in dogs. Notably, women were significantly more likely to be seropositive for A. phagocytophilum than men (p = 0.0289). Dogs from the Serra do Apon community more commonly had A. phagocytophilum (p = 0.0477) and B. microti (p = 0.0448) than those from the other areas. To the best of our knowledge, this is the first study to report human exposure to A. phagocytophilum and the ocurrence of B. microti in Brazil. The antibody level of vector-borne diseases in humans is a public health concern, particularly in vulnerable populations and rural areas. The dogs were universally hosted Rhipicephalus sanguineus ticks, suggesting their possible role in transmission. Thus, further epidemiological surveillance studies should be conducted in vulnerable populations to mitigate the impact of such zoonotic diseases.
|
| Subject | |
| Genre | |
| Type | |
| Language |
eng
|
| Date Available |
2025-05-12
|
| Provider |
Vancouver : University of British Columbia Library
|
| Rights |
CC BY 4.0
|
| DOI |
10.14288/1.0448845
|
| URI | |
| Affiliation | |
| Citation |
Pathogens 14 (4): 318 (2025)
|
| Publisher DOI |
10.3390/pathogens14040318
|
| Peer Review Status |
Reviewed
|
| Scholarly Level |
Faculty; Researcher
|
| Rights URI | |
| Aggregated Source Repository |
DSpace
|
Item Media
Item Citations and Data
Rights
CC BY 4.0