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Advancements in Carbohydrate Scaffold Synthesis : Exploring Prins Cyclization Methodology Dubbu, Sateesh; Jampani, Santhi

Abstract

The synthesis of natural and unconventional compounds with carbohydrate structures is of great interest to glycochemists due to their vital biological roles. In recent years, there has been significant progress in developing direct and indirect synthetic strategies for constructing sugar moieties. Among these methods, the Prins reaction, employing homoallylic alcohols and carbonyl compounds, has proven invaluable for directly creating sugar skeletons. This review discusses approaches for crafting carbohydrate frameworks using the Prins reaction, utilizing both carbohydrate and non-carbohydrate starting materials.

Item Metadata

Title
Advancements in Carbohydrate Scaffold Synthesis : Exploring Prins Cyclization Methodology
Creator
Dubbu, Sateesh; Jampani, Santhi
Publisher
Multidisciplinary Digital Publishing Institute
Date Issued
2025-01-03
Description
The synthesis of natural and unconventional compounds with carbohydrate structures is of great interest to glycochemists due to their vital biological roles. In recent years, there has been significant progress in developing direct and indirect synthetic strategies for constructing sugar moieties. Among these methods, the Prins reaction, employing homoallylic alcohols and carbonyl compounds, has proven invaluable for directly creating sugar skeletons. This review discusses approaches for crafting carbohydrate frameworks using the Prins reaction, utilizing both carbohydrate and non-carbohydrate starting materials.
Subject
carbohydrates; Prins reaction; 2-deoxysuagrs; homoallylic alcohols; rare sugars
Genre
Article
Type
Text
Language
eng
Date Available
2025-04-14
Provider
Vancouver : University of British Columbia Library
Rights
CC BY 4.0
DOI
10.14288/1.0448407
URI
http://hdl.handle.net/2429/90666
Affiliation
Science, Faculty of; Non UBC; Earth, Ocean and Atmospheric Sciences, Department of
Citation
Reactions 6 (1): 3 (2025)
Publisher DOI
10.3390/reactions6010003
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Rights URI
https://creativecommons.org/licenses/by/4.0/
Aggregated Source Repository
DSpace

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CC BY 4.0