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Novel Magnetic Resonance Imaging Tools for Hypertrophic Cardiomyopathy Risk Stratification Alajmi, Fahad; Kang, Mehima; Dundas, James; Haenel, Alexander; Parker, Jeremy; Blanke, Philipp; Coghlan, Fionn; Khoo, John King; Bin Zaid, Abdulaziz A.; Singh, Amrit; Heydari, Bobby; Yeung, Darwin; Roston, Thomas; Ong, Kevin; Leipsic, Jonathon; Laksman, Zachary

Abstract

Hypertrophic cardiomyopathy (HCM) is a common genetic disorder with a well described risk of sudden cardiac death; however, risk stratification has remained a challenge. Recently, novel parameters in cardiac magnetic resonance imaging (CMR) have shown promise in helping to improve upon current risk stratification paradigms. In this manuscript, we have reviewed novel CMR risk markers and their utility in HCM. The results of the review showed that T1, extracellular volume, CMR feature tracking, and other miscellaneous novel CMR variables have the potential to improve sudden death risk stratification and may have additional roles in diagnosis and prognosis. The strengths and weaknesses of these imaging techniques, and their potential utility and implementation in HCM risk stratification are discussed.

Item Metadata

Title
Novel Magnetic Resonance Imaging Tools for Hypertrophic Cardiomyopathy Risk Stratification
Creator
Alajmi, Fahad; Kang, Mehima; Dundas, James; Haenel, Alexander; Parker, Jeremy; Blanke, Philipp; Coghlan, Fionn; Khoo, John King; Bin Zaid, Abdulaziz A.; Singh, Amrit; Heydari, Bobby; Yeung, Darwin; Roston, Thomas; Ong, Kevin; Leipsic, Jonathon; Laksman, Zachary
Contributor
UBC Division of Cardiology & Cardiovascular Surgery; Center for Cardiovascular Innovation
Publisher
Multidisciplinary Digital Publishing Institute
Date Issued
2024-01-30
Description
Hypertrophic cardiomyopathy (HCM) is a common genetic disorder with a well described risk of sudden cardiac death; however, risk stratification has remained a challenge. Recently, novel parameters in cardiac magnetic resonance imaging (CMR) have shown promise in helping to improve upon current risk stratification paradigms. In this manuscript, we have reviewed novel CMR risk markers and their utility in HCM. The results of the review showed that T1, extracellular volume, CMR feature tracking, and other miscellaneous novel CMR variables have the potential to improve sudden death risk stratification and may have additional roles in diagnosis and prognosis. The strengths and weaknesses of these imaging techniques, and their potential utility and implementation in HCM risk stratification are discussed.
Subject
hypertrophic cardiomyopathy; cardiac magnetic resonance imaging; prognosis; T1; T2; feature tracking
Genre
Article
Type
Text
Language
eng
Date Available
2024-03-12
Provider
Vancouver : University of British Columbia Library
Rights
CC BY 4.0
DOI
10.14288/1.0440666
URI
http://hdl.handle.net/2429/87556
Affiliation
Medicine, Faculty of; Non UBC; Anesthesiology, Pharmacology and Therapeutics, Department of; Radiology, Department of
Citation
Life 14 (2): 200 (2024)
Publisher DOI
10.3390/life14020200
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Rights URI
https://creativecommons.org/licenses/by/4.0/
Aggregated Source Repository
DSpace

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CC BY 4.0