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Topical AHA in Dermatology: Formulations, Mechanisms of Action, Efficacy, and Future Perspectives Karwal, Kanwarpreet; Mukovozov, Ilya

Abstract

The utilization of topical formulations containing alpha hydroxy acids (AHAs) has garnered considerable attention. This review summarizes the effectiveness of the most common topical AHA formulations, including mechanisms of action and future research directions. AHAs have a dramatic impact on diverse skin conditions, enhancing texture and stimulating collagen synthesis. Uncertainties persist regarding optimal concentration, pH, and vehicle for maximum efficacy. Advancements in formulation technologies offer opportunities for AHA penetration and stability. Understanding mechanisms is vital for skincare optimization. The review covers AHAs, their concentrations, formulation considerations, safety measures, and future directions.

Item Metadata

Title
Topical AHA in Dermatology: Formulations, Mechanisms of Action, Efficacy, and Future Perspectives
Creator
Karwal, Kanwarpreet; Mukovozov, Ilya
Publisher
Multidisciplinary Digital Publishing Institute
Date Issued
2023-09-19
Description
The utilization of topical formulations containing alpha hydroxy acids (AHAs) has garnered considerable attention. This review summarizes the effectiveness of the most common topical AHA formulations, including mechanisms of action and future research directions. AHAs have a dramatic impact on diverse skin conditions, enhancing texture and stimulating collagen synthesis. Uncertainties persist regarding optimal concentration, pH, and vehicle for maximum efficacy. Advancements in formulation technologies offer opportunities for AHA penetration and stability. Understanding mechanisms is vital for skincare optimization. The review covers AHAs, their concentrations, formulation considerations, safety measures, and future directions.
Subject
AHA; glycolic acid; lactic acid; citric acid; photoaging; hyperpigmentation; acne
Genre
Article
Type
Text
Language
eng
Date Available
2023-10-27
Provider
Vancouver : University of British Columbia Library
Rights
CC BY 4.0
DOI
10.14288/1.0437390
URI
http://hdl.handle.net/2429/86362
Affiliation
Medicine, Faculty of; Non UBC; Dermatology and Skin Science, Department of
Citation
Cosmetics 10 (5): 131 (2023)
Publisher DOI
10.3390/cosmetics10050131
Peer Review Status
Reviewed
Scholarly Level
Faculty
Rights URI
https://creativecommons.org/licenses/by/4.0/
Aggregated Source Repository
DSpace

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Rights

CC BY 4.0