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TAVR for All? The Surgical Perspective Zhang, Xiling; Puehler, Thomas; Frank, Derk; Sathananthan, Janarthanan; Sellers, Stephanie; Meier, David; Both, Marcus; Blanke, Philipp; Seoudy, Hatim; Saad, Mohammed; Müller, Oliver J.; Sondergaard, Lars; Lutter, Georg

Abstract

In spite of the noninferiority of transcatheter aortic valve replacement (TAVR) in high- and intermediate-risk patients, there are still obstacles that need to be overcome before the procedure is further expanded and clinically integrated. The lack of evidence on the long-term durability of the bioprostheses used for TAVR remains of particular concern. In addition, surgery may be preferred over TAVR in patients with bicuspid aortic valve (BAV) or with concomitant pathologies such as other valve diseases (mitral regurgitation/tricuspid regurgitation), aortopathy, and coronary artery disease. In this review, we discuss and summarize relevant data from clinical trials, current trends, and remaining obstacles, and provide our perspective on the indications for the expansion of TAVR.

Item Metadata

Title
TAVR for All? The Surgical Perspective
Creator
Zhang, Xiling; Puehler, Thomas; Frank, Derk; Sathananthan, Janarthanan; Sellers, Stephanie; Meier, David; Both, Marcus; Blanke, Philipp; Seoudy, Hatim; Saad, Mohammed; Müller, Oliver J.; Sondergaard, Lars; Lutter, Georg
Contributor
St. Paul's Hospital (Vancouver, B.C.). Centre for Heart Valve Innovation; Providence Health Care (Vancouver, B.C.). Research Institute; Centre for Cardiovascular Innovation
Publisher
Multidisciplinary Digital Publishing Institute
Date Issued
2022-07-12
Description
In spite of the noninferiority of transcatheter aortic valve replacement (TAVR) in high- and intermediate-risk patients, there are still obstacles that need to be overcome before the procedure is further expanded and clinically integrated. The lack of evidence on the long-term durability of the bioprostheses used for TAVR remains of particular concern. In addition, surgery may be preferred over TAVR in patients with bicuspid aortic valve (BAV) or with concomitant pathologies such as other valve diseases (mitral regurgitation/tricuspid regurgitation), aortopathy, and coronary artery disease. In this review, we discuss and summarize relevant data from clinical trials, current trends, and remaining obstacles, and provide our perspective on the indications for the expansion of TAVR.
Subject
aortic valve stenosis; transcatheter aortic valve replacement (TAVR); transcatheter aortic valve implantation (TAVI); surgical aortic valve replacement (SAVR); low risk; intermediate risk; high risk
Genre
Article
Type
Text
Language
eng
Date Available
2022-12-15
Provider
Vancouver : University of British Columbia Library
Rights
CC BY 4.0
DOI
10.14288/1.0422638
URI
http://hdl.handle.net/2429/83428
Affiliation
Medicine, Faculty of; Non UBC; Radiology, Department of
Citation
Journal of Cardiovascular Development and Disease 9 (7): 223 (2022)
Publisher DOI
10.3390/jcdd9070223
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Rights URI
https://creativecommons.org/licenses/by/4.0/
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CC BY 4.0