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Cerebellar Differences after Rehabilitation in Children with Developmental Coordination Disorder Gill, Kamaldeep; Lang, Donna J.; Zwicker, Jill G.

Abstract

Developmental coordination disorder (DCD) affects a child’s ability to learn motor skills. Cognitive Orientation to daily Occupational Performance (CO-OP) is one of the recommended treatments to help achieve functional motor goals. The purpose of this study was to determine if CO-OP intervention induces functional improvements and structural changes in the cerebellum of children with DCD. Using a randomized waitlist-controlled trial, we investigated the effects of CO-OP intervention on cerebellar volume in 47 children with DCD (8–12 years old). Outcome measures included the Canadian Occupational Performance Measure, Performance Quality Rating Scale (PQRS), and Bruininks–Oseretsky Test of Motor Proficiency-2. The SUIT toolbox was used to carry out voxel-based morphometry using T1-weighted MRI scans. Children with DCD showed improved motor outcomes and increased gray matter volume in the brainstem, right crus II, bilateral lobules VIIIb, and left lobule IX following CO-OP. Significant associations were found between PQRS scores and regional gray matter changes in the brainstem, right crus II, right lobule VIIb, right and left lobule VIIIb, and vermis IX. Given the improved motor and brain outcomes with CO-OP, it is recommended that children with DCD be referred for this rehabilitation intervention.

Item Metadata

Title
Cerebellar Differences after Rehabilitation in Children with Developmental Coordination Disorder
Creator
Gill, Kamaldeep; Lang, Donna J.; Zwicker, Jill G.
Contributor
Children's Hospital (Vancouver, B.C.). Research Institute; Children's Hospital (Vancouver, B.C.). Research Institute. Brain, Behaviour & Development
Publisher
Multidisciplinary Digital Publishing Institute
Date Issued
2022-06-29
Description
Developmental coordination disorder (DCD) affects a child’s ability to learn motor skills. Cognitive Orientation to daily Occupational Performance (CO-OP) is one of the recommended treatments to help achieve functional motor goals. The purpose of this study was to determine if CO-OP intervention induces functional improvements and structural changes in the cerebellum of children with DCD. Using a randomized waitlist-controlled trial, we investigated the effects of CO-OP intervention on cerebellar volume in 47 children with DCD (8–12 years old). Outcome measures included the Canadian Occupational Performance Measure, Performance Quality Rating Scale (PQRS), and Bruininks–Oseretsky Test of Motor Proficiency-2. The SUIT toolbox was used to carry out voxel-based morphometry using T1-weighted MRI scans. Children with DCD showed improved motor outcomes and increased gray matter volume in the brainstem, right crus II, bilateral lobules VIIIb, and left lobule IX following CO-OP. Significant associations were found between PQRS scores and regional gray matter changes in the brainstem, right crus II, right lobule VIIb, right and left lobule VIIIb, and vermis IX. Given the improved motor and brain outcomes with CO-OP, it is recommended that children with DCD be referred for this rehabilitation intervention.
Subject
developmental coordination disorder; motor skills disorder; rehabilitation; CO-OP; voxel-based morphometry; cerebellum; neuroplasticity
Genre
Article
Type
Text
Language
eng
Date Available
2022-12-02
Provider
Vancouver : University of British Columbia Library
Rights
CC BY 4.0
DOI
10.14288/1.0422368
URI
http://hdl.handle.net/2429/83344
Affiliation
Medicine, Faculty of; Alumni; Occupational Science and Occupational Therapy, Department of; Pediatrics, Department of; Radiology, Department of
Citation
Brain Sciences 12 (7): 856 (2022)
Publisher DOI
10.3390/brainsci12070856
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher
Rights URI
https://creativecommons.org/licenses/by/4.0/
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CC BY 4.0