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Dynamic Morphometric Changes in Degenerative Lumbar Spondylolisthesis : A Pilot Study of Upright Magnetic Resonance Imaging Charest-Morin, Raphaële; Zhang, Honglin; Shewchuk, Jason; Wilson, David R.; Phillips, Amy E.; Bond, Michael; Street, John T.

Abstract

The objectives of this study were to (a) develop a standing MRI imaging protocol, tolerable to symptomatic patients with degenerative spondylolisthesis (DLS), and (b) to evaluate the morphometric changes observed in DLS patients in both supine and standing postures. Patients with single level, Meyerding grade 1 DLS undergoing surgery at a single institution between November 2015 to May 2017 were consented. Patients were imaged in the supine and standing positions in a 0.5T vertically open MRI scanner (MROpen, Paramed, Genoa, Italy) with sagittal and axial T2 images. The morphometric parameters measured were: cross-sectional area of the thecal sac (CSA), lateral recess height, disc height, degree of anterolisthesis, disc angle, lumbar lordosis, the presence of facet effusion and restabilization signs. Measures from both postures were compared using paired T-test. Associations of posture with the magnitude of change in the various measurements was determined using Pearson correlation or paired T-test when appropriate. All fourteen patients (mean age 64.4 years) included tolerated standing for the time required for image acquisition. All measurements with the exception of lumbar lordosis and disk height showed a statistically significant difference between the postures (p <0.05). In the standing position, CSA and lateral recess height were reduced by 28% and 50%, respectively. There was no relationship between the change in CSA of the thecal sac and any measures. Standing images acquired in an upright MRI scanner demonstrated postural changes associated with Meyerding grade 1 DLS and images acquisition was tolerated in all patients.

Item Metadata

Title
Dynamic Morphometric Changes in Degenerative Lumbar Spondylolisthesis : A Pilot Study of Upright Magnetic Resonance Imaging
Creator
Charest-Morin, Raphaële; Zhang, Honglin; Shewchuk, Jason; Wilson, David R.; Phillips, Amy E.; Bond, Michael; Street, John T.
Contributor
Centre for Hip Health and Mobility
Publisher
Elsevier
Date Issued
2021-07-10
Description
The objectives of this study were to (a) develop a standing MRI imaging protocol, tolerable to symptomatic patients with degenerative spondylolisthesis (DLS), and (b) to evaluate the morphometric changes observed in DLS patients in both supine and standing postures. Patients with single level, Meyerding grade 1 DLS undergoing surgery at a single institution between November 2015 to May 2017 were consented. Patients were imaged in the supine and standing positions in a 0.5T vertically open MRI scanner (MROpen, Paramed, Genoa, Italy) with sagittal and axial T2 images. The morphometric parameters measured were: cross-sectional area of the thecal sac (CSA), lateral recess height, disc height, degree of anterolisthesis, disc angle, lumbar lordosis, the presence of facet effusion and restabilization signs. Measures from both postures were compared using paired T-test. Associations of posture with the magnitude of change in the various measurements was determined using Pearson correlation or paired T-test when appropriate. All fourteen patients (mean age 64.4 years) included tolerated standing for the time required for image acquisition. All measurements with the exception of lumbar lordosis and disk height showed a statistically significant difference between the postures (p <0.05). In the standing position, CSA and lateral recess height were reduced by 28% and 50%, respectively. There was no relationship between the change in CSA of the thecal sac and any measures. Standing images acquired in an upright MRI scanner demonstrated postural changes associated with Meyerding grade 1 DLS and images acquisition was tolerated in all patients.
Subject
Upright MRI; Standing MRI; Degenerative spondylolisthesis; Cross-sectional area of the thecal sac; Instability
Genre
Article; Postprint
Type
Text
Language
eng
Date Available
2022-10-26
Provider
Vancouver : University of British Columbia Library
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
DOI
10.14288/1.0421531
URI
http://hdl.handle.net/2429/82980
Affiliation
Medicine, Faculty of; Orthopaedic Surgery, Department of; Radiology, Department of
Citation
Charest-Morin, R et al. Dynamic morphometric changes in degenerative lumbar spondylolisthesis: A pilot study of upright magnetic resonance imaging. J Clin Neurosci. 2021 Sep;91:152-158.
Publisher DOI
10.1016/j.jocn.2021.06.027
Peer Review Status
Reviewed
Scholarly Level
Faculty; Researcher; Other
Rights URI
http://creativecommons.org/licenses/by-nc-nd/4.0/
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Attribution-NonCommercial-NoDerivatives 4.0 International