Open Collections

UBC Faculty Research and Publications

Predictors of health-related quality of life following injury in childhood and adolescence : a pooled analysis Dipnall, Joanna F; Rivara, Frederick P; Lyons, Ronan A; Ameratunga, Shanthi; Brussoni, Mariana; Lecky, Fiona E; Bradley, Clare; Beck, Ben; Lyons, Jane; Schneeberg, Amy; et al.

Abstract

Background Injury is a leading contributor to the global disease burden in children and places children at risk for adverse and lasting impacts on their health-related quality of life (HRQoL) and development. This study aimed to identify key predictors of HRQoL following injury in childhood and adolescence. Methods Data from 2259 injury survivors (<18 years when injured) were pooled from four longitudinal cohort studies (Australia, Canada, UK, USA) from the paediatric Validating Injury Burden Estimates Study (VIBES-Junior). Outcomes were the Paediatric Quality of Life Inventory (PedsQL) total, physical, psychosocial functioning scores at 1, 3–4, 6, 12, 24 months postinjury. Results Mean PedsQL total score increased with higher socioeconomic status and decreased with increasing age. It was lower for transport-related incidents, ≥1 comorbidities, intentional injuries, spinal cord injury, vertebral column fracture, moderate/severe traumatic brain injury and fracture of patella/tibia/fibula/ankle. Mean PedsQL physical score was lower for females, fracture of femur, fracture of pelvis and burns. Mean PedsQL psychosocial score was lower for asphyxiation/non-fatal submersion and muscle/tendon/dislocation injuries. Conclusions Postinjury HRQoL was associated with survivors’ socioeconomic status, intent, mechanism of injury and comorbidity status. Patterns of physical and psychosocial functioning postinjury differed according to sex and nature of injury sustained. The findings improve understanding of the long-term individual and societal impacts of injury in the early part of life and guide the prioritisation of prevention efforts, inform health and social service planning to help reduce injury burden, and help guide future Global Burden of Disease estimates.

Item Metadata

Title
Predictors of health-related quality of life following injury in childhood and adolescence : a pooled analysis
Creator
Dipnall, Joanna F; Rivara, Frederick P; Lyons, Ronan A; Ameratunga, Shanthi; Brussoni, Mariana; Lecky, Fiona E; Bradley, Clare; Beck, Ben; Lyons, Jane; Schneeberg, Amy; Harrison, James E; Gabbe, Belinda J
Contributor
B.C. Injury Research and Prevention Unit; Children's Hospital (Vancouver, B.C.). Research Institute
Publisher
BMJ Publishing Group
Date Issued
2021
Description
Background Injury is a leading contributor to the global disease burden in children and places children at risk for adverse and lasting impacts on their health-related quality of life (HRQoL) and development. This study aimed to identify key predictors of HRQoL following injury in childhood and adolescence. Methods Data from 2259 injury survivors (<18 years when injured) were pooled from four longitudinal cohort studies (Australia, Canada, UK, USA) from the paediatric Validating Injury Burden Estimates Study (VIBES-Junior). Outcomes were the Paediatric Quality of Life Inventory (PedsQL) total, physical, psychosocial functioning scores at 1, 3–4, 6, 12, 24 months postinjury. Results Mean PedsQL total score increased with higher socioeconomic status and decreased with increasing age. It was lower for transport-related incidents, ≥1 comorbidities, intentional injuries, spinal cord injury, vertebral column fracture, moderate/severe traumatic brain injury and fracture of patella/tibia/fibula/ankle. Mean PedsQL physical score was lower for females, fracture of femur, fracture of pelvis and burns. Mean PedsQL psychosocial score was lower for asphyxiation/non-fatal submersion and muscle/tendon/dislocation injuries. Conclusions Postinjury HRQoL was associated with survivors’ socioeconomic status, intent, mechanism of injury and comorbidity status. Patterns of physical and psychosocial functioning postinjury differed according to sex and nature of injury sustained. The findings improve understanding of the long-term individual and societal impacts of injury in the early part of life and guide the prioritisation of prevention efforts, inform health and social service planning to help reduce injury burden, and help guide future Global Burden of Disease estimates.
Subject
Children and youth (0-19); Outdoor/risky play
Genre
Article
Type
Text
Language
eng
Date Available
2022-08-04
Provider
Vancouver : University of British Columbia Library
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
DOI
10.14288/1.0416576
URI
http://hdl.handle.net/2429/82258
Affiliation
Medicine, Faculty of; Population and Public Health (SPPH), School of; Pediatrics, Department of; Non UBC
Citation
Dipnall JF, Rivara FP, Lyons RA, et al Predictors of health-related quality of life following injury in childhood and adolescence: a pooled analysisInjury Prevention Published Online First: 22 December 2021.
Publisher DOI
10.1136/injuryprev-2021-044309
Peer Review Status
Unreviewed
Scholarly Level
Faculty; Researcher
Rights URI
https://creativecommons.org/licenses/by-nc-nd/4.0/
Aggregated Source Repository
DSpace

Item Media

Item Citations and Data

Rights

Attribution-NonCommercial-NoDerivatives 4.0 International