UBC Faculty Research and Publications

Non-invasive brain stimulation combined with psychosocial intervention for depression: a systematic review and meta-analysis He, Jiali; Tang, Yiling; Lin, Jingxia; Faulkner, Guy E. J., 1970-; Tsang, Hector W. H.; Chan, Sunny H. W.

Abstract

Objectives This review investigates the efficacy and safety of non-invasive brain stimulation (NIBS) combined with psychosocial intervention on depressive symptoms. Materials and methods We systematically searched five electronic databases from their inception to June 2021: PubMed, Embase, PsycINFO, Web of Science, and Medline. Randomized or non-randomized clinical trials in which NIBS plus psychosocial intervention was compared to control conditions in people with depressive symptoms were included. Results A total of 17 eligible studies with 660 participants were included. The meta-analysis results showed that NIBS combined with psychosocial therapy had a positive effect on moderate to severe depression ([SMD = − 0.46, 95%CI (− 0.90, − 0.02), I2 = 73%, p 

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Attribution 4.0 International (CC BY 4.0)