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Developments in the integration and application of terahertz spectroscopy with microfluidics Alfihed, Salman; Holzman, Jonathan; Foulds, Ian G.
Abstract
This work presents an overview of terahertz (THz) spectroscopy with a focus on its implementation within microfluidic platforms. Such platforms are of great interest because they can enable label-free and reagent-free sensing. However, they must be implemented with thought towards the incorporated materials and structures as they can greatly impact the bandwidth, frequency resolution, signal-to-noise ratio, and dynamic range of the measurements. This review explores such relationships with insight given on the design and material considerations for the effective integration of THz spectroscopy in microfluidic platforms. The review also describes recent work on the application of THz spectroscopy to biomaterial analyses on increasing scales, targeting DNA, proteins, cells, and tissues.
Item Metadata
Title |
Developments in the integration and application of terahertz spectroscopy with microfluidics
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Creator | |
Publisher |
Elsevier
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Date Issued |
2020
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Description |
This work presents an overview of terahertz (THz) spectroscopy with a focus on its
implementation within microfluidic platforms. Such platforms are of great interest because they
can enable label-free and reagent-free sensing. However, they must be implemented with thought
towards the incorporated materials and structures as they can greatly impact the bandwidth,
frequency resolution, signal-to-noise ratio, and dynamic range of the measurements. This review
explores such relationships with insight given on the design and material considerations for the
effective integration of THz spectroscopy in microfluidic platforms. The review also describes
recent work on the application of THz spectroscopy to biomaterial analyses on increasing scales,
targeting DNA, proteins, cells, and tissues.
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Subject | |
Genre | |
Type | |
Language |
eng
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Date Available |
2022-10-01
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Provider |
Vancouver : University of British Columbia Library
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Rights |
Attribution-NonCommercial-NoDerivatives 4.0 International
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DOI |
10.14288/1.0413760
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URI | |
Affiliation | |
Citation |
S. Alfihed, J. F. Holzman, and I. G. Foulds, "Developments in the integration and application of terahertz spectroscopy with microfluidics," Biosensors and Bioelectronics, vol. 165, pp. 1-11, 2020.
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Publisher DOI |
10.1016/j.bios.2020.112393
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Peer Review Status |
Reviewed
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Scholarly Level |
Faculty; Researcher
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Rights URI | |
Aggregated Source Repository |
DSpace
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Item Media
Item Citations and Data
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International