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The Effects of Aerobic-Resistance Training and Broccoli Supplementation on Plasma Dectin-1 and Insulin Resistance in Males with Type 2 Diabetes Saeidi, Ayoub; Soltani, Mohammad; Daraei, Ali; Nohbaradar, Hanieh; Haghighi, Marjan Mosalman; Khosravi, Nikoo; Johnson, Kelly E.; Laher, Ismail; Hackney, Anthony C.; VanDusseldorp, Trisha A.; Zouhal, Hassane

Abstract

Background: This study aimed to evaluate the effects of a combination of aerobic-resistance training (CARET) and broccoli supplementation on dectin-1 levels and insulin resistance in men with type 2 diabetes mellitus (T2D). Methods: Forty-four males with T2D were randomly allocated to four groups (n = 11 each group): CARET + broccoli supplement (TS), CARET + placebo (TP), control + broccoli supplement (S), and control + placebo (CP). CARET was performed three days per week for 12 weeks. TS and S groups received 10 g of broccoli supplement per day for 12 weeks. All variables were assessed at baseline and 12 weeks. Results: Plasma dectin-1 levels were decreased in TS and TP groups compared with the CP group (p < 0.05). Cardiometabolic risk factors showed significant reductions in TP and TS groups compared to S and CP groups (p < 0.05). Conclusion: The combination of CARET and broccoli supplementation produced the largest improvements in insulin resistance and dectin-1 and other complications of T2D.

Item Metadata

Title
The Effects of Aerobic-Resistance Training and Broccoli Supplementation on Plasma Dectin-1 and Insulin Resistance in Males with Type 2 Diabetes
Creator
Saeidi, Ayoub; Soltani, Mohammad; Daraei, Ali; Nohbaradar, Hanieh; Haghighi, Marjan Mosalman; Khosravi, Nikoo; Johnson, Kelly E.; Laher, Ismail; Hackney, Anthony C.; VanDusseldorp, Trisha A.; Zouhal, Hassane
Publisher
Multidisciplinary Digital Publishing Institute
Date Issued
2021-09-09
Description
Background: This study aimed to evaluate the effects of a combination of aerobic-resistance training (CARET) and broccoli supplementation on dectin-1 levels and insulin resistance in men with type 2 diabetes mellitus (T2D). Methods: Forty-four males with T2D were randomly allocated to four groups (n = 11 each group): CARET + broccoli supplement (TS), CARET + placebo (TP), control + broccoli supplement (S), and control + placebo (CP). CARET was performed three days per week for 12 weeks. TS and S groups received 10 g of broccoli supplement per day for 12 weeks. All variables were assessed at baseline and 12 weeks. Results: Plasma dectin-1 levels were decreased in TS and TP groups compared with the CP group (p < 0.05). Cardiometabolic risk factors showed significant reductions in TP and TS groups compared to S and CP groups (p < 0.05). Conclusion: The combination of CARET and broccoli supplementation produced the largest improvements in insulin resistance and dectin-1 and other complications of T2D.
Subject
aerobic-strength training; concurrent exercise training; HOMA-IR; inflammation; body mass index; fat percent; broccoli
Genre
Article
Type
Text
Language
eng
Date Available
2021-10-14
Provider
Vancouver : University of British Columbia Library
Rights
CC BY 4.0
DOI
10.14288/1.0402524
URI
http://hdl.handle.net/2429/79971
Affiliation
Health and Social Development, Faculty of (Okanagan); Medicine, Faculty of; Non UBC; Anesthesiology, Pharmacology and Therapeutics, Department of; Health and Exercise Sciences, School of (Okanagan)
Citation
Nutrients 13 (9): 3144 (2021)
Publisher DOI
10.3390/nu13093144
Peer Review Status
Reviewed
Scholarly Level
Faculty
Rights URI
https://creativecommons.org/licenses/by/4.0/
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CC BY 4.0