UBC Faculty Research and Publications

Recent Advancements in Polythiophene-Based Materials and their Biomedical, Geno Sensor and DNA Detection Mousavi, Seyyed Mojtaba; Hashemi, Seyyed Alireza; Bahrani, Sonia; Yousefi, Khadije; Behbudi, Gity; Babapoor, Aziz; Omidifar, Navid; Lai, Chin Wei; Gholami, Ahmad; Chiang, Wei-Hung

Abstract

In this review, the unique properties of intrinsically conducting polymer (ICP) in biomedical engineering fields are summarized. Polythiophene and its valuable derivatives are known as potent materials that can broadly be applied in biosensors, DNA, and gene delivery applications. Moreover, this material plays a basic role in curing and promoting anti-HIV drugs. Some of the thiophene’s derivatives were chosen for different experiments and investigations to study their behavior and effects while binding with different materials and establishing new compounds. Many methods were considered for electrode coating and the conversion of thiophene to different monomers to improve their functions and to use them for a new generation of novel medical usages. It is believed that polythiophenes and their derivatives can be used in the future as a substitute for many old-fashioned ways of creating chemical biosensors polymeric materials and also drugs with lower side effects yet having a more effective response. It can be noted that syncing biochemistry with biomedical engineering will lead to a new generation of science, especially one that involves high-efficiency polymers. Therefore, since polythiophene can be customized with many derivatives, some of the novel combinations are covered in this review.

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