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The Role of Ultrasound for the Personalized Botulinum Toxin Treatment of Cervical Dystonia Fietzek, Urban M.; Nene, Devavrat; Schramm, Axel; Appel-Cresswell, Silke; Košutzká, Zuzana; Walter, Uwe; Wissel, Jörg; Berweck, Steffen; Chouinard, Sylvain; Bäumer, Tobias

Abstract

The visualization of the human body has frequently been groundbreaking in medicine. In the last few years, the use of ultrasound (US) imaging has become a well-established procedure for botulinum toxin therapy in people with cervical dystonia (CD). It is now undisputed among experts that some of the most relevant muscles in this indication can be safely injected under visual US guidance. This review will explore the method from basic technical considerations, current evidence to conceptual developments of the phenomenology of cervical dystonia. We will review the implications of introducing US to our understanding of muscle function and anatomy of common cervical dystonic patterns. We suggest a flow chart for the use of US to achieve a personalized treatment of people with CD. Thus, we hope to contribute a resource that is useful in clinical practice and that stimulates the ongoing development of this valuable technique.

Item Metadata

Title
The Role of Ultrasound for the Personalized Botulinum Toxin Treatment of Cervical Dystonia
Creator
Fietzek, Urban M.; Nene, Devavrat; Schramm, Axel; Appel-Cresswell, Silke; Košutzká, Zuzana; Walter, Uwe; Wissel, Jörg; Berweck, Steffen; Chouinard, Sylvain; Bäumer, Tobias
Contributor
Djavad Mowafaghian Centre for Brain Health
Publisher
Multidisciplinary Digital Publishing Institute
Date Issued
2021-05-20
Description
The visualization of the human body has frequently been groundbreaking in medicine. In the last few years, the use of ultrasound (US) imaging has become a well-established procedure for botulinum toxin therapy in people with cervical dystonia (CD). It is now undisputed among experts that some of the most relevant muscles in this indication can be safely injected under visual US guidance. This review will explore the method from basic technical considerations, current evidence to conceptual developments of the phenomenology of cervical dystonia. We will review the implications of introducing US to our understanding of muscle function and anatomy of common cervical dystonic patterns. We suggest a flow chart for the use of US to achieve a personalized treatment of people with CD. Thus, we hope to contribute a resource that is useful in clinical practice and that stimulates the ongoing development of this valuable technique.
Subject
botulinum toxin; cervical dystonia; ultrasound
Genre
Article
Type
Text
Language
eng
Date Available
2021-05-26
Provider
Vancouver : University of British Columbia Library
Rights
CC BY 4.0
DOI
10.14288/1.0398173
URI
http://hdl.handle.net/2429/78462
Affiliation
Medicine, Faculty of; Other UBC; Non UBC; Medicine, Department of; Neurology, Division of
Citation
Toxins 13 (5): 365 (2021)
Publisher DOI
10.3390/toxins13050365
Peer Review Status
Reviewed
Scholarly Level
Faculty
Rights URI
https://creativecommons.org/licenses/by/4.0/
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CC BY 4.0