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Development of Point-of-Care Biosensors for COVID-19 Choi, Jane Ru
Abstract
Coronavirus disease 2019 (COVID-19) outbreak has become a global pandemic. The deleterious effects of coronavirus have prompted the development of diagnostic tools to manage the spread of disease. While conventional technologies such as quantitative real time polymerase chain reaction (qRT-PCR) have been broadly used to detect COVID-19, they are time-consuming, labor-intensive and are unavailable in remote settings. Point-of-care (POC) biosensors, including chip-based and paper-based biosensors are typically low-cost and user-friendly, which offer tremendous potential for rapid medical diagnosis. This mini review article discusses the recent advances in POC biosensors for COVID-19. First, the development of POC biosensors which are made of polydimethylsiloxane (PDMS), papers, and other flexible materials such as textile, film, and carbon nanosheets are reviewed. The advantages of each biosensors along with the commercially available COVID-19 biosensors are highlighted. Lastly, the existing challenges and future perspectives of developing robust POC biosensors to rapidly identify and manage the spread of COVID-19 are briefly discussed.
Item Metadata
Title |
Development of Point-of-Care Biosensors for COVID-19
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Creator | |
Contributor | |
Publisher |
Frontiers
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Date Issued |
2020-05-27
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Description |
Coronavirus disease 2019 (COVID-19) outbreak has become a global pandemic.
The deleterious effects of coronavirus have prompted the development of diagnostic
tools to manage the spread of disease. While conventional technologies such as
quantitative real time polymerase chain reaction (qRT-PCR) have been broadly used
to detect COVID-19, they are time-consuming, labor-intensive and are unavailable in
remote settings. Point-of-care (POC) biosensors, including chip-based and paper-based
biosensors are typically low-cost and user-friendly, which offer tremendous potential for
rapid medical diagnosis. This mini review article discusses the recent advances in POC
biosensors for COVID-19. First, the development of POC biosensors which are made of
polydimethylsiloxane (PDMS), papers, and other flexible materials such as textile, film,
and carbon nanosheets are reviewed. The advantages of each biosensors along with
the commercially available COVID-19 biosensors are highlighted. Lastly, the existing
challenges and future perspectives of developing robust POC biosensors to rapidly
identify and manage the spread of COVID-19 are briefly discussed.
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Subject | |
Genre | |
Type | |
Language |
eng
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Date Available |
2021-04-14
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Provider |
Vancouver : University of British Columbia Library
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Rights |
Attribution 4.0 International
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DOI |
10.14288/1.0396712
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URI | |
Affiliation | |
Citation |
Choi JR (2020) Development of Point-of-Care Biosensors for COVID-19. Front. Chem. 8:517.
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Publisher DOI |
10.3389/fchem.2020.00517
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Peer Review Status |
Reviewed
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Scholarly Level |
Postdoctoral
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Copyright Holder |
Author
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Rights URI | |
Aggregated Source Repository |
DSpace
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Item Media
Item Citations and Data
Rights
Attribution 4.0 International