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Aiming for a shorter time to diagnosis: pediatric eosinophilic esophagitis in British Columbia Jia, Jocelyn; Chan, Edmond S.; Avinashi, Vishal; Hsu, Elaine; Ko, Hin H.; Soller, Lianne

Abstract

Longer time to diagnosis for patients with eosinophilic esophagitis can lead to adverse patient outcomes, but the length of diagnostic delay has not been quantified for patients with eosinophilic esophagitis in Canada. Our study defines the time to diagnosis (TTD) for pediatric patients with eosinophilic esophagitis in British Columbia and identifies factors that predict increased time to diagnosis. The median TTD was 21 months (1.75 years; IQR = 7, 45) with a median age at EoE diagnosis of 105 months (8.75 years; IQR = 44, 156). Caucasians experienced significantly longer TTD compared to other ethnicities (24 months (IQR = 7, 52) and 12 months (IQR = 4.5, 23) respectively, p = 0.008). Caucasian ethnicity (p = 0.037) and older age at the time of diagnosis (p = 0.006) predicted increased TTD. Our model explained 7.9% (Adjusted R² = 0.079) of the total variance for our cohort.

Item Metadata

Title
Aiming for a shorter time to diagnosis: pediatric eosinophilic esophagitis in British Columbia
Creator
Jia, Jocelyn; Chan, Edmond S.; Avinashi, Vishal; Hsu, Elaine; Ko, Hin H.; Soller, Lianne
Contributor
Children's Hospital (Vancouver, B.C.). Research Institute; St. Paul's Hospital (Vancouver, B.C.)
Publisher
BioMed Central
Date Issued
2020-10-14
Description
Longer time to diagnosis for patients with eosinophilic esophagitis can lead to adverse patient outcomes, but the length of diagnostic delay has not been quantified for patients with eosinophilic esophagitis in Canada. Our study defines the time to diagnosis (TTD) for pediatric patients with eosinophilic esophagitis in British Columbia and identifies factors that predict increased time to diagnosis. The median TTD was 21 months (1.75 years; IQR = 7, 45) with a median age at EoE diagnosis of 105 months (8.75 years; IQR = 44, 156). Caucasians experienced significantly longer TTD compared to other ethnicities (24 months (IQR = 7, 52) and 12 months (IQR = 4.5, 23) respectively, p = 0.008). Caucasian ethnicity (p = 0.037) and older age at the time of diagnosis (p = 0.006) predicted increased TTD. Our model explained 7.9% (Adjusted R² = 0.079) of the total variance for our cohort.
Subject
Eosinophilic esophagitis; Pediatric; Diagnosis; Delay
Genre
Article
Type
Text
Language
eng
Date Available
2020-10-15
Provider
Vancouver : University of British Columbia Library
Rights
Attribution 4.0 International (CC BY 4.0)
DOI
10.14288/1.0394746
URI
http://hdl.handle.net/2429/76290
Affiliation
Medicine, Faculty of; Other UBC; Non UBC; Medicine, Department of; Pediatrics, Department of
Citation
Allergy, Asthma & Clinical Immunology. 2020 Oct 14;16(1):88
Publisher DOI
10.1186/s13223-020-00486-2
Peer Review Status
Reviewed
Scholarly Level
Faculty
Copyright Holder
The Author(s)
Rights URI
http://creativecommons.org/licenses/by/4.0/
Aggregated Source Repository
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Rights

Attribution 4.0 International (CC BY 4.0)