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Effects of Ramadan Intermittent Fasting on Gut Hormones and Body Composition in Males with Obesity Zouhal, Hassane; Bagheri, Reza; Triki, Raoua; Saeidi, Ayoub; Wong, Alexei; Hackney, Anthony C.; Laher, Ismail; Suzuki, Katsuhiko; Ben Abderrahman, Abderraouf

Abstract

We studied the effects of Ramadan intermittent fasting (RIF) on gut hormones (leptin, glucagon-like peptide-1 (GLP-1), peptide YY (PYY), cholecystokinin (CCK), and ghrelin) in males with obesity. Thirty sedentary males were randomly allocated to either an experimental group (EG, n = 15) or a control group (CG, n = 15). The EG group completed their Ramadan fasting rituals (30 days), whereas the CG continued with their normal daily habits. Blood samples were collected at four time points: 24 h before the start of Ramadan (T0), on the 15th day of Ramadan (T1), the day after the end of Ramadan (T2) and 21 days after Ramadan (T3). There were significant pre-to-post improvements for leptin (p = 0.01, d = 1.52), GLP-1 (p = 0.022, d = 0.75), PYY (p = 0.031, d = 0.69) and CCK (p = 0.027, d = 0.81) in the EG, with no interaction effect for ghrelin (p = 0.74; d = 0.008). No significant changes (p > 0.05) occurred in plasma volume variations (ΔPV) after RIF in both EG (−0.03 ± 0.01%) and CG (0.06 ± 0.07%). RIF represents an effective strategy to modify appetite-regulating hormones, leading to improved body composition indices and reduced obesity.

Item Metadata

Title
Effects of Ramadan Intermittent Fasting on Gut Hormones and Body Composition in Males with Obesity
Creator
Zouhal, Hassane; Bagheri, Reza; Triki, Raoua; Saeidi, Ayoub; Wong, Alexei; Hackney, Anthony C.; Laher, Ismail; Suzuki, Katsuhiko; Ben Abderrahman, Abderraouf
Publisher
Multidisciplinary Digital Publishing Institute
Date Issued
2020-08-03
Description
We studied the effects of Ramadan intermittent fasting (RIF) on gut hormones (leptin, glucagon-like peptide-1 (GLP-1), peptide YY (PYY), cholecystokinin (CCK), and ghrelin) in males with obesity. Thirty sedentary males were randomly allocated to either an experimental group (EG, n = 15) or a control group (CG, n = 15). The EG group completed their Ramadan fasting rituals (30 days), whereas the CG continued with their normal daily habits. Blood samples were collected at four time points: 24 h before the start of Ramadan (T0), on the 15th day of Ramadan (T1), the day after the end of Ramadan (T2) and 21 days after Ramadan (T3). There were significant pre-to-post improvements for leptin (p = 0.01, d = 1.52), GLP-1 (p = 0.022, d = 0.75), PYY (p = 0.031, d = 0.69) and CCK (p = 0.027, d = 0.81) in the EG, with no interaction effect for ghrelin (p = 0.74; d = 0.008). No significant changes (p > 0.05) occurred in plasma volume variations (ΔPV) after RIF in both EG (−0.03 ± 0.01%) and CG (0.06 ± 0.07%). RIF represents an effective strategy to modify appetite-regulating hormones, leading to improved body composition indices and reduced obesity.
Subject
obese; overweight; gut hormones; fasting; body composition
Genre
Article
Type
Text
Language
eng
Date Available
2020-08-07
Provider
Vancouver : University of British Columbia Library
Rights
CC BY 4.0
DOI
10.14288/1.0392661
URI
http://hdl.handle.net/2429/75389
Affiliation
Medicine, Faculty of; Non UBC; Anesthesiology, Pharmacology and Therapeutics, Department of
Citation
International Journal of Environmental Research and Public Health 17 (15): 5600 (2020)
Publisher DOI
10.3390/ijerph17155600
Peer Review Status
Reviewed
Scholarly Level
Faculty
Rights URI
https://creativecommons.org/licenses/by/4.0/
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CC BY 4.0