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Variability of Water-Soluble Forms of Choline Concentrations in Human Milk during Storage, after Pasteurization, and among Women Moukarzel, Sara; Wiedeman, Alejandra M.; Soberanes, Lynda S.; Dyer, Roger A.; Innis, Sheila M.; Lamers, Yvonne

Abstract

Choline is critical for infant development and mother’s milk is the sole source of choline for fully breastfed infants until six months of age. Human milk choline consists to 85% of water-soluble forms of choline including free choline (FC), phosphocholine (PhosC), and glycerophosphocholine (GPC). Donor milk requires safe handling procedures such as cold storage and pasteurization. However, the stability of water-soluble forms of choline during these processes is not known. The objectives of this research were to determine the effect of storage and pasteurization on milk choline concentration, and the diurnal intra- and inter-individual variability of water-soluble choline forms. Milk samples were collected from healthy women who were fully breastfeeding a full-term, singleton infant

Item Metadata

Title
Variability of Water-Soluble Forms of Choline Concentrations in Human Milk during Storage, after Pasteurization, and among Women
Creator
Moukarzel, Sara; Wiedeman, Alejandra M.; Soberanes, Lynda S.; Dyer, Roger A.; Innis, Sheila M.; Lamers, Yvonne
Contributor
Children's Hospital (Vancouver, B.C.). Research Institute; University of British Columbia. Food, Nutrition and Health Program
Publisher
Multidisciplinary Digital Publishing Institute
Date Issued
2019-12-11
Description
Choline is critical for infant development and mother’s milk is the sole source of choline for fully breastfed infants until six months of age. Human milk choline consists to 85% of water-soluble forms of choline including free choline (FC), phosphocholine (PhosC), and glycerophosphocholine (GPC). Donor milk requires safe handling procedures such as cold storage and pasteurization. However, the stability of water-soluble forms of choline during these processes is not known. The objectives of this research were to determine the effect of storage and pasteurization on milk choline concentration, and the diurnal intra- and inter-individual variability of water-soluble choline forms. Milk samples were collected from healthy women who were fully breastfeeding a full-term, singleton infant
Subject
human milk; donor milk; choline; phosphocholine; storage; pasteurization; milk banking; pumping; breastfeeding; lactation
Genre
Article
Type
Text
Language
eng
Date Available
2020-01-08
Provider
Vancouver : University of British Columbia Library
Rights
CC BY 4.0
DOI
10.14288/1.0388193
URI
http://hdl.handle.net/2429/73218
Affiliation
Medicine, Faculty of; Other UBC; Pediatrics, Department of
Citation
Nutrients 11 (12): 3024 (2019)
Publisher DOI
10.3390/nu11123024
Peer Review Status
Reviewed
Scholarly Level
Faculty
Rights URI
https://creativecommons.org/licenses/by/4.0/
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CC BY 4.0