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Management of Primary and Recurrent Clostridium difficile Infection: An Update Chai, Jocelyn; Lee, Christine H.

Abstract

Background: Clostridium difficile infection (CDI) is one of the most common healthcare-associated infections (HAI) in the United States and Canada, and incidence rates have increased worldwide in recent decades. Currently, antibiotics are the mainstay treatments for both primary and recurrent CDI, but their efficacy is limited, prompting further therapies to be developed. Aim: This review summarizes current and emerging therapies in CDI management including antibiotics, fecal microbiota transplantation, monoclonal antibodies, spore-based therapies, and vaccinations.

Item Metadata

Title
Management of Primary and Recurrent Clostridium difficile Infection: An Update
Creator
Chai, Jocelyn; Lee, Christine H.
Publisher
Multidisciplinary Digital Publishing Institute
Date Issued
2018-06-30
Description
Background: Clostridium difficile infection (CDI) is one of the most common healthcare-associated infections (HAI) in the United States and Canada, and incidence rates have increased worldwide in recent decades. Currently, antibiotics are the mainstay treatments for both primary and recurrent CDI, but their efficacy is limited, prompting further therapies to be developed. Aim: This review summarizes current and emerging therapies in CDI management including antibiotics, fecal microbiota transplantation, monoclonal antibodies, spore-based therapies, and vaccinations.
Subject
Clostridium difficile infection; Healthcare-associated infections; Antibiotics; Fecal microbiota transplantation
Genre
Article
Type
Text
Language
eng
Date Available
2019-06-24
Provider
Vancouver : University of British Columbia Library
Rights
CC BY 4.0
DOI
10.14288/1.0379551
URI
http://hdl.handle.net/2429/70745
Affiliation
Medicine, Faculty of; Non UBC; Pathology and Laboratory Medicine, Department of
Citation
Antibiotics 7 (3): 54 (2018)
Publisher DOI
10.3390/antibiotics7030054
Peer Review Status
Reviewed
Scholarly Level
Faculty
Rights URI
https://creativecommons.org/licenses/by/4.0/
Aggregated Source Repository
DSpace

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Rights

CC BY 4.0