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Prevalence and Predictors of Low Vitamin B6 Status in Healthy Young Adult Women in Metro Vancouver Ho, Chia-ling; Quay, Teo A. W.; Devlin, Angela M.; Lamers, Yvonne

Abstract

Low periconceptional vitamin B6 (B6) status has been associated with an increased risk of preterm birth and early pregnancy loss. Given many pregnancies are unplanned; it is important for women to maintain an adequate B6 status throughout reproductive years. There is limited data on B6 status in Canadian women. This study aimed to assess the prevalence of B6 deficiency and predictors of B6 status in young adult women in Metro Vancouver. We included a convenience sample of young adult non-pregnant women (19–35 years; n = 202). Vitamin B6 status was determined using fasting plasma concentrations of pyridoxal 5’-phosphate (PLP). Mean (95% confidence interval) plasma PLP concentration was 61.0 (55.2, 67.3) nmol/L. The prevalence of B6 deficiency (plasma PLP < 20 nmol/L) was 1.5% and that of suboptimal B6 status (plasma PLP = 20–30 nmol/L) was 10.9%. Body mass index, South Asian ethnicity, relative dietary B6 intake, and the use of supplemental B6 were significant predictors of plasma PLP. The combined 12.4% prevalence of B6 deficiency and suboptimal status was lower than data reported in US populations and might be due to the high socioeconomic status of our sample. More research is warranted to determine B6 status in the general Canadian population.

Item Metadata

Title
Prevalence and Predictors of Low Vitamin B6 Status in Healthy Young Adult Women in Metro Vancouver
Creator
Ho, Chia-ling; Quay, Teo A. W.; Devlin, Angela M.; Lamers, Yvonne
Contributor
University of British Columbia. Food, Nutrition and Health Program; Children's Hospital (Vancouver, B.C.). Research Institute
Publisher
Multidisciplinary Digital Publishing Institute
Date Issued
2016-09-01
Description
Low periconceptional vitamin B6 (B6) status has been associated with an increased risk of preterm birth and early pregnancy loss. Given many pregnancies are unplanned; it is important for women to maintain an adequate B6 status throughout reproductive years. There is limited data on B6 status in Canadian women. This study aimed to assess the prevalence of B6 deficiency and predictors of B6 status in young adult women in Metro Vancouver. We included a convenience sample of young adult non-pregnant women (19–35 years; n = 202). Vitamin B6 status was determined using fasting plasma concentrations of pyridoxal 5’-phosphate (PLP). Mean (95% confidence interval) plasma PLP concentration was 61.0 (55.2, 67.3) nmol/L. The prevalence of B6 deficiency (plasma PLP < 20 nmol/L) was 1.5% and that of suboptimal B6 status (plasma PLP = 20–30 nmol/L) was 10.9%. Body mass index, South Asian ethnicity, relative dietary B6 intake, and the use of supplemental B6 were significant predictors of plasma PLP. The combined 12.4% prevalence of B6 deficiency and suboptimal status was lower than data reported in US populations and might be due to the high socioeconomic status of our sample. More research is warranted to determine B6 status in the general Canadian population.
Subject
Vitamin B6; Pyridoxal 5’-phosphate; Suboptimal status; Deficiency; Ethnicity; Dietary intake; Supplement use; Women; Periconceptional
Genre
Article
Type
Text
Language
eng
Date Available
2019-05-27
Provider
Vancouver : University of British Columbia Library
Rights
CC BY 4.0
DOI
10.14288/1.0379027
URI
http://hdl.handle.net/2429/70347
Affiliation
Land and Food Systems, Faculty of; Medicine, Faculty of; Other UBC; Non UBC; Pediatrics, Department of
Citation
Nutrients 8 (9): 538 (2016)
Publisher DOI
10.3390/nu8090538
Peer Review Status
Reviewed
Scholarly Level
Faculty
Rights URI
https://creativecommons.org/licenses/by/4.0/
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CC BY 4.0