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Short-Term Low-Carbohydrate High-Fat Diet in Healthy Young Males Renders the Endothelium Susceptible to Hyperglycemia-Induced Damage, An Exploratory Analysis Durrer, Cody; Lewis, Nia; Wan, Zhongxiao; Ainslie, Philip N., 1974-; Jenkins, Nathan T.; Little, Jonathan P.

Abstract

Postprandial hyperglycemia has been linked to elevated risk of cardiovascular disease. Endothelial dysfunction and/or damage may be one of the mechanisms through which this occurs. In this exploratory study, we determined whether acute glucose ingestion would increase markers of endothelial damage/activation and impair endothelial function before and after a short-term low-carbohydrate high-fat diet (HFD) designed to induce relative glucose intolerance. Nine healthy young males (body mass index 23.2 ± 2 kg/m2) consumed a 75 g glucose drink before and

Item Metadata

Title
Short-Term Low-Carbohydrate High-Fat Diet in Healthy Young Males Renders the Endothelium Susceptible to Hyperglycemia-Induced Damage, An Exploratory Analysis
Creator
Durrer, Cody; Lewis, Nia; Wan, Zhongxiao; Ainslie, Philip N., 1974-; Jenkins, Nathan T.; Little, Jonathan P.
Publisher
Multidisciplinary Digital Publishing Institute
Date Issued
2019-02-26
Description
Postprandial hyperglycemia has been linked to elevated risk of cardiovascular disease. Endothelial dysfunction and/or damage may be one of the mechanisms through which this occurs. In this exploratory study, we determined whether acute glucose ingestion would increase markers of endothelial damage/activation and impair endothelial function before and after a short-term low-carbohydrate high-fat diet (HFD) designed to induce relative glucose intolerance. Nine healthy young males (body mass index 23.2 ± 2 kg/m2) consumed a 75 g glucose drink before and
Subject
High-fat diet; Microparticles; EMPs; Flow-mediated dilation; FMD
Genre
Article
Type
Text
Language
eng
Date Available
2019-04-23
Provider
Vancouver : University of British Columbia Library
Rights
CC BY 4.0
DOI
10.14288/1.0378351
URI
http://hdl.handle.net/2429/69826
Affiliation
Health and Social Development, Faculty of (Okanagan); Non UBC; Health and Exercise Sciences, School of (Okanagan)
Citation
Nutrients 11 (3): 489 (2019)
Publisher DOI
10.3390/nu11030489
Peer Review Status
Reviewed
Scholarly Level
Faculty
Rights URI
https://creativecommons.org/licenses/by/4.0/
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CC BY 4.0