UBC Faculty Research and Publications

Cocaine/crack use is not associated with fibrosis progression measured by AST-to-Platelet Ratio Index in HIV-HCV co-infected patients: a cohort study Martel-Laferrière, Valérie; Nitulescu, Roy; Cox, Joseph; Cooper, Curtis; Tyndall, Mark; Rouleau, Danielle; Walmsley, Sharon; Wong, Leo; Klein, Marina B

Abstract

Background: Cocaine and crack use has been associated with HIV and HCV infections, but its consequences on HCV progression have not been well established. We analyzed the impact of cocaine/crack use on liver fibrosis progression in a cohort of HIV-HCV co-infected patients. Methods: A Canadian multicenter prospective cohort study followed 1238 HIV-HCV co-infected persons every 6 months between 2003 and 2013. Data were analyzed from 573 patients with positive HCV RNA, not on HCV treatment, without significant liver fibrosis (AST-to-Platelet Ratio Index (APRI)

Item Media

Item Citations and Data

Rights

Attribution 4.0 International (CC BY 4.0)

Usage Statistics