UBC Faculty Research and Publications

Early Outcomes in Children with Antineutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV) Morishita, Kimberly; Moorthy, Lakshmi N.; Lubieniecka, Joanna M.; Twilt, Marinka; Yeung, Rae S.M.; Toth, Mary B.; Shenoi, Susan; Ristic, Goran; Nielsen, Susan M.; Li, Suzanne C.; Lee, Tzielan; Lawson, Erica; Kostik, Mikhail; Klein-Gitelman, Marisa; Huber, Adam M.; Hersh, Aimee O.; Foell, Dirk; Elder, Melissa E.; Eberhard, Barbara A.; Dancey, Paul; Charuvanij, Sirirat; Benseler, Susanne; Cabral, David A.


Objective: To characterize early disease course in childhood onset antineutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) and 12-month outcomes. Methods: Eligible subjects were children diagnosed with GPA, MPA, EGPA, and ANCA-positive pauci-immune glomerulonephritis before their eighteenth birthday and entered into The Pediatric Vasculitis Initiative (PedVas) study. The primary outcome was remission (Pediatric Vasculitis Activity Score (PVAS) = 0 with corticosteroid dose (CS)

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