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Making smart investment decisions in clinical research Bansback, Nick; Keystone, Edward; O’Dell, James; Phibbs, Ciaran S.; Hannagan, Keri; Brophy, Mary; Anis, Aslam H. (Aslam Hayat), 1959-

Abstract

A recent trial in rheumatoid arthritis found an inexpensive, but infrequently used, combination of therapies is neither inferior nor less safe than an expensive biologic drug. If the trial had been conducted over 10 years ago, arguably 100’s of millions of dollars since spent on biologics could have been released to other, more effective treatments. Given the ever increasing number of trials proposed, this commentary uses the trial as an example to challenge payers and research funders to make smarter investments in clinical research to save potential future costs. Trial registration: NCT00405275 , registered 29 November 2006

Item Metadata

Title
Making smart investment decisions in clinical research
Creator
Bansback, Nick; Keystone, Edward; O’Dell, James; Phibbs, Ciaran S.; Hannagan, Keri; Brophy, Mary; Anis, Aslam H. (Aslam Hayat), 1959-
Contributor
Centre for Health Evaluation & Outcome Sciences; St. Paul’s Hospital (Vancouver, B.C.)
Publisher
BioMed Central
Date Issued
2015-12-29
Description
A recent trial in rheumatoid arthritis found an inexpensive, but infrequently used, combination of therapies is neither inferior nor less safe than an expensive biologic drug. If the trial had been conducted over 10 years ago, arguably 100’s of millions of dollars since spent on biologics could have been released to other, more effective treatments. Given the ever increasing number of trials proposed, this commentary uses the trial as an example to challenge payers and research funders to make smarter investments in clinical research to save potential future costs. Trial registration: NCT00405275 , registered 29 November 2006
Subject
Rheumatoid arthritis; Randomized trials; Economics
Genre
Article
Type
Text
Language
eng
Date Available
2017-05-10
Provider
Vancouver : University of British Columbia Library
Rights
Attribution 4.0 International (CC BY 4.0)
DOI
10.14288/1.0347384
URI
http://hdl.handle.net/2429/61602
Affiliation
Medicine, Faculty of; Other UBC; Non UBC; Population and Public Health (SPPH), School of
Citation
Trials. 2015 Dec 29;16(1):590
Publisher DOI
10.1186/s13063-015-1123-1
Peer Review Status
Reviewed
Scholarly Level
Faculty
Copyright Holder
Bansback et al.
Rights URI
http://creativecommons.org/licenses/by/4.0/
Aggregated Source Repository
DSpace

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Rights

Attribution 4.0 International (CC BY 4.0)