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Ulysses - an application for the projection of molecular interactions across species Kemmer, Danielle; Huang, Yong; Shah, Sohrab P.; Lim, Jonathan; Brumm, Jochen; Yuen, Macaire M.; Ling, John; Xu, Tao; Wasserman, Wyeth W.; Ouellette, B. F. F.

Abstract

We developed Ulysses as a user-oriented system that uses a process called Interolog Analysis for the parallel analysis and display of protein interactions detected in various species. Ulysses was designed to perform such Interolog Analysis by the projection of model organism interaction data onto homologous human proteins, and thus serves as an accelerator for the analysis of uncharacterized human proteins. The relevance of projections was assessed and validated against published reference collections. All source code is freely available, and the Ulysses system can be accessed via a web interface http://www.cisreg.ca/ulysses .

Item Metadata

Title
Ulysses - an application for the projection of molecular interactions across species
Creator
Kemmer, Danielle; Huang, Yong; Shah, Sohrab P.; Lim, Jonathan; Brumm, Jochen; Yuen, Macaire M.; Ling, John; Xu, Tao; Wasserman, Wyeth W.; Ouellette, B. F. F.
Contributor
Michael Smith Laboratories
Publisher
BioMed Central
Date Issued
2005-12-02
Description
We developed Ulysses as a user-oriented system that uses a process called Interolog Analysis for the parallel analysis and display of protein interactions detected in various species. Ulysses was designed to perform such Interolog Analysis by the projection of model organism interaction data onto homologous human proteins, and thus serves as an accelerator for the analysis of uncharacterized human proteins. The relevance of projections was assessed and validated against published reference collections. All source code is freely available, and the Ulysses system can be accessed via a web interface http://www.cisreg.ca/ulysses .
Genre
Article
Type
Text
Language
eng
Date Available
2015-11-17
Provider
Vancouver : University of British Columbia Library
Rights
Attribution 4.0 International (CC BY 4.0)
DOI
10.14288/1.0228393
URI
http://hdl.handle.net/2429/55390
Affiliation
Computer Science, Department of; Medical Genetics, Department of; Medicine, Faculty of; Molecular Medicine and Therapeutics, Centre for; Science, Faculty of
Citation
Genome Biology. 2005 Dec 02;6(12):R106
Publisher DOI
10.1186/gb-2005-6-12-r106
Peer Review Status
Reviewed
Scholarly Level
Faculty
Copyright Holder
Kemmer et al..
Rights URI
http://creativecommons.org/licenses/by/4.0/
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DSpace

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Attribution 4.0 International (CC BY 4.0)